نتایج جستجو برای: regulated gene 2
تعداد نتایج: 3464676 فیلتر نتایج به سال:
Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): Science Centre (NCN) and Internal source Medical University Warsaw. Introduction Regular physical exercise is analogous to improved cardiovascular health increased longevity. However, if in excess it can act as a double edged sword. Acute bouts extreme activity trigger complex mole...
Background: The seladin-1 (selective Alzheimer disease indicator-1), also known as DHCR24, is a gene found to be down-regulated in brain region affected by Alzheimer disease (AD). Whereas, hair follicle stem cells (HFSC), which are affected in with neurogenic potential, it might to hypothesize that this multipotent cell compartment is the predominant source of seladin-1. Our aim was to evaluate...
background : 5-fluorouracil could lead to a decline in fertility in caenorhabditis elegans. the aim of this study was to describe the mechanisms underlying such an altered fertility phenotype and to illustrate the specific genes and path-ways that are involved in the related phenotypic changes in c. elegans. methods : we isolated total rna from the samples and used a new method called digital g...
A Study for Expression and Biological Function of N-myc Downstream Regulated Gene 2 in Breast Cancer
Longevity is regulated by the daf-2 gene network in Caenorhabditis elegans. Mutations in the daf-2 gene, which encodes a member of the insulin receptor family, confer the life extension (Age) phenotype and the constitutive dauer (a growth-arrested larval form specialized for dispersal) formation phenotype. The Age phenotype is mutually potentiated by two life extension mutations in the daf-2 ge...
In this study, we verified the effects of 2-aza-8-oxohypoxanthine (AOH) on human epidermal cell proliferation by performing DNA microarray analysis. Cell was assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, which measures mitochondrial respiration in normal keratinocyte (NHEK) cells. Gene expression levels were determined analysis 177 genes involved skin aging ...
Background and purpose: Gastric cancer is the most common cancer associated with high mortality worldwide. One of the genes that is down-regulated in gastric cancer, is the SIRT3 that encodes the histone deacetylase enzyme. There is a variable number tandem repeat (VNTR) polymorphism in the intron 5 of SIRT3 gene and evidence shows that expression of SIRT3 gene increases by increase in the numb...
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