The prevailing view on multiple sclerosis etiopathogenesis has been challenged by the suggested new entity chronic cerebrospinal venous insufficiency. To test this hypothesis, we studied 21 relapsing-remitting multiple sclerosis cases and 20 healthy controls with phasecontrast magnetic resonance imaging. In addition, in multiple sclerosis cases we performed contrastenhanced magnetic resonance a...

juvenile fibroadenoma is an uncommon histologic variant of fibroadenoma that frequently shows a remarkable and rapid growth. the development of a carcinoma within a fibroadenoma, either in situ or invasive, is a rare condition. we encountered a 36-year-old woman with a palpable mass in the right breast. the radiologic findings were indicative of a fibroadenoma in the breast. sonographic guided ...

background diffusion-weighted imaging (dwi) is a form of magnetic resonance imaging (mri) based on measuring the random brownian motion of water molecules within the biological tissues and is particularly useful in tumor characterization. objectives the purpose of this study was to evaluate the diagnostic value of dw mri and the apparent diffusion coefficient (adc) for preoperative grading of a...

Multiple sclerosis (MS) is a chronic disabling autoimmune disorder of the central nervous system histopathologically characterized by inflammation, multifocal demyelination, axonal damage and neuronal loss. Focal intensive demyelination and white matter infiltration by lymphocytes and mononuclear cells are pathological hallmarks of the disease (Ferguson et al., 1997; Lucchinetti et al., 2000). ...

Multiple sclerosis (MS) is the most common chronic-inflammatory demyelinating disease of the central nervous system (CNS) [1]. In addition to clinical presentation and examination of the cerebrospinal fluid, imaging, in particular magnetic resonance imaging (MRI), plays an important role in the diagnosis and disease monitoring of MS [2, 3]. The increased relevance of MRI of the brain and spinal...

Objective: To investigate the correlation between cumulative doses of gadolinium-based contrast agents and increased signal intensity (SI) in dentate nucleus (DN) globus pallidus (GP). Methods: Our retrospective trial involved 21 multiple sclerosis patients (11 women, 10 men; mean age: 39.21±10.24, range: 20 to 57 years) who underwent a serial number cranial magnetic resonance imaging (MRI) exa...

BACKGROUND Multiple sclerosis is a rare neurological disorder in black Africans. In Nigeria it had been difficult to confirm suspected cases due to the paucity of diagnostic facilities. The availability of magnetic resonance imaging has enabled an increased confidence in making the diagnosis. METHOD This is a case report of a 40- year old Nigerian farmer of the Igbo ethnic group living in a r...

BACKGROUND We have previously shown that the inducible kinin B(1) receptor is expressed on T lymphocytes during relapses and progression in multiple sclerosis. OBJECTIVE To evaluate the correlation between the expression of B1 receptor on peripheral blood mononuclear cells derived from patients who have multiple sclerosis with serial, clinical magnetic resonance imaging and immunological stud...

Background: The present study aimed to compare the clinical efficacy and safety profile of Ziferon and Betaferon. Objectives: In total, 41 consecutive patients with relapsing forms of Multiple Sclerosis (MS) were selected from the MS outpatient clinic affiliated to Tehran University of Medical Sciences. The patients were randomly assigned into two groups. Methods: Each group either received Z...