نتایج جستجو برای: secretory product
تعداد نتایج: 307146 فیلتر نتایج به سال:
int-2 was discovered as a proto-oncogene transcriptionally activated by MMTV proviral insertion during mammary tumorigenesis in the mouse. Sequence analysis showed int-2 to be a member of the fibroblast growth factor family of genes. In normal breast and most other adult mouse tissues, int-2 expression was not detected except for low levels in brain and testis. However, using in situ hybridizat...
Excess secretory products fuse with lysosomes ells known to spew secretory protein granules had been helpful in deciphering and defining the secretory pathway. But what happened when secretion systems were turned off? Lysosomes were known to degrade foreign proteins taken up by cells and even autodigest intracellular membranous structures—but what was the fate of excess endogenous protein? To a...
Cytochemical tests for several marker enzymes were applied to liver tissue and to the three Golgi fractions (GF(1), GF(2), GF(3)) separated by the procedure of Ehrenreich et al. from liver homogenates of alcohol-treated rats. 5'-Nucleotidase (AMPase) reaction product was found in all three fractions but in different locations: It occurred along the inside of the membrane of VLDL-filled vacuoles...
Using histopathological analysis of semi-thin sections stained with toluidine blue, we observed profound pathological changes in the islets of Langerhans of hamsters infected with the scrapie agent (strain 139H). These included cytoplasmic vesicles, nuclear swelling, and vacuolization in the islet cells. Two types of vacuolization were seen. "Localized vacuolization" (LV) has a distinct edge an...
although research on adult subjects has demonstrated a positive correlation between humor and increased concentrations of secretory immunoglobulin a, the literature has not addressed whether humor might have a similar effect on children. fifth grade student volunteers (n= 190) at elementary schools in hamadan were randomly assigned to treatment and control groups. the study compared secretory i...
in this thesis, at first we investigate the bounded inverse theorem on fuzzy normed linear spaces and study the set of all compact operators on these spaces. then we introduce the notions of fuzzy boundedness and investigate a new norm operators and the relationship between continuity and boundedness. and, we show that the space of all fuzzy bounded operators is complete. finally, we define...
Lasp-1 is a regulated phosphoprotein within the cAMP signaling pathway in the gastric parietal cell.
Activation of the cAMP signaling pathway is correlated with increased secretory-related events in a wide variety of cell types including the gastric parietal cell. Within this pathway, as well as in other intracellular signaling pathways, protein phosphorylation serves as a major downstream regulatory mechanism. However, although agonist and cAMP-dependent activation of cAMP-dependent protein k...
Genetic analysis of protein secretion in Escherichia coli has identified secY/prlA and secA as components of the secretory apparatus. We have examined the roles of the secY(prlA) gene product (an integral membrane protein) and the soluble secA gene product in translocation of OmpA and alkaline phosphatase precursors in an in vitro system. The protein translocation defect of the secY24 mutation ...
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