Inflammation, oxidative stress, obesity, infection, hyperlipidemia, hypertension, and diabetes are the main causes of atherosclerosis, which in long term lead to hardening arteries. In current study, we reviewed recent findings mechanism sesame its active compounds sesamin sesamolin regulates on atherosclerosis. Sesame can decrease lipid peroxidation affect enzymes, control balance status body....

CONTEXT Sesamin (Ses) from Sesamun indicum seeds has potent antioxidants and anti-inflammatory effects. OBJECTIVE This study focused on the antioxidant and anti-inflammatory effects of Ses on Carbon tetrachloride (CCl4)-induced hepatic fibrosis in experimental rats and the potential mechanism underlying the activation of NF-kB pathway. MATERIALS AND METHODS Hepatic fibrosis was induced by i...