the use of animal models in modeling of human genetic disease has many advantages. in some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and physiology of humans and animals. isogenic human disease models are a population of cells that are selected or engineered to model a specific genetic disease, in vitro. they ar...

A common method to study the dynamic behavior of macroeconomic variables is using linear time series models; however, they are unable to explain nonlinear behavior of the series. Given the dependency between stock market and derivatives, the behavior of the underlying asset price can be modeled using Markov switching process properties and the economic regime significance. In this paper, a two-...

BACKGROUND Relative to Western women, Korean women show several differences in breast-related characteristics, including higher rates of dense breasts and small breasts. We investigated how mammographic composition and breast size affect the glandular dose during full-field digital mammography (FFDM) in Korean women using a radiation dose management system. METHODS From June 1 to June 30, 201...

We study how to perform model selection for time series data where millions of candidate ARMA models may be eligible for selection.We propose a feasible computingmethod based on theGibbs sampler. By thismethodmodel selection is performed through a random sample generation algorithm, and given amodel of fixed dimension the parameter estimation is done through the maximum likelihood method. Our m...