When trypan blue is injected intravenously, the animal appears blue within a few minutes, not only in its integument, but in the internal organs as well. 12 or more hours after the administration of the dye, there are innumerable granules within macrophages and other colloidopexic cells, easily demonstrable by ordinary histological technique. But the animal is blue long before such granules are...

fond of statements such as "buffer action is ultimately dependent on a spacetime frame of reference." The main fault of this book, however, is that so much of it is outdated. It seems surprising that a text concerned with rational drug design should lack a discussion of protein structure and does not list deoxyribonucleic and ribonucleic acids in its index. Sulfonamide action is discussed witho...

The physical basis of contrast and image formation in electron micrography is considered in relation to the possibility of recording selective chemical effects on cell components. A technology of selective microchemical analysis, equivalent to differential staining, is suggested as practicable in electron micrography. Electron pictures of bacteria after exposure to salts of heavy metals have sh...