OBJECTIVES To study the impact of obesity, age and varicocele on sexual hormones of adult and elderly men. MATERIALS AND METHODS 875 men who were screened for prostate cancer were enrolled in this study. Data recorded comprised age, body mass index (BMI), serum levels of total testosterone (TT), free testosterone (FT), sex hormone-binding globulin (SHBG), luteinizing hormone (LH) and follicul...

There are some studies showing that varicoceles may cause injury to the testicle outside of the typical symptoms of infertility and pain. In a study of 835 men, 325 of which had a palpable varicocele demonstrated that those with a varicocele had significantly lower testosterone levels that those without, 416 versus 469 ng dl −1. 9 This effect of testosterone does not seem to be affected by grad...

The goal of surgical treatment of the varicocele is to occlude the refluxing venous drainage to the testis while maintaining normal testicular function. Many surgical techniques for treating varicoceles have been described. We aim to present an adolescent case with varicocele treated by simple laparoscopic ligation technique using intracorporeal knot-tying.

Objective(s): Increased levels of nitric oxide (NO) in the testicular veins of people suffering from varicocele have already been reported. However, the role of NO-synthase (NOS) isozymes and their inhibitors have not been extensively studied. We aimed to evaluate the inhibitory effects of aminoguanidine (AG), on sperm motility, vitality, and mitochondrial membrane potential (MMP) in varicoceli...

Varicocele repair is mainly indicated in young adult patients with clinical palpable varicocele and abnormal semen parameters. Varicocele treatment is associated with a significant improvement in sperm concentration, motility, morphology, and pregnancy rate. Antegrade scrotal sclerotherapy (ASS) represented one of the main alternatives to the traditional inguinal or suprainguinal surgical ligat...

A consensus needs to be reached on a rational approach to infertile men with varicocele-associated nonobstructive azoospermia. Future studies are warranted to understand the mechanism behind the variable influence of varicocele on testicular function, which causes partial or complete damage of spermatogenesis in some cases and leaves it unaltered in others.

Varicocele affects approximately 35%-40% of men presenting for an infertility evaluation. There is fair evidence indicating that surgical repair of clinical varicocele improves semen parameters, decreases seminal oxidative stress and sperm DNA fragmentation, and increases the chances of natural conception. However, it is unclear whether performing varicocelectomy in men with clinical varicocele...

Varicocelectomy is the most commonly performed operation for the treatment of male infertility. Varicocele is found in approximately 15% of general male population and in 40% of men with infertility. The treatment of varicocele is not necessary unless the varicocele causes pathological spermiogram, difficulties and intense testicular volume at work and walking, also in children with varicocele ...