نتایج جستجو برای: synaptic p
تعداد نتایج: 1327773 فیلتر نتایج به سال:
The development of the nervous system is based on genetic as well as epigenetic mechanisms: among the latter a prominent role is played both by chemical factors (neurotrophins being an important class) and by the electrical impulse activity. The result of these developmental interactions is the complex set of synaptic connections that characterize the adult nervous system. One remarkable aspect...
Background and Objective: Evaluation of degenerative changes of motoneurons and their related synapses can be useful in understanding the mechanisms of neurodegenerative diseases and their potential treatment. The present electron microscopic and immunohistochemical study investigates the axotomy-induced...
Solid-state synaptic transistor achieves greatest memory retention capacity for AI computing systems to date
BACKGROUND/AIMS Recent studies have implicated a region on chromosome 1q21-23, including the NOS1AP gene, in susceptibility to schizophrenia. However, replication studies have been inconsistent, a fact that could partly relate to the marked psychopathological heterogeneity of schizophrenia. The aim of this study is to evaluate association of polymorphisms in the NOS1AP gene region to schizophre...
We have studied the effect of isoflurane on potassium-evoked release and high-affinity uptake of -aminobutyric acid (GABA) in rat cortical synaptosomes. Isoflurane 1.5% and 3% increased calcium-dependent release by 38% and 36% of control values, respectively (P 0.05). Calcium-independent release was reduced correspondingly by 24% and 26% (P 0.05). Highaffinity uptake of GABA was not affected by...
Synaptic integration is a prominent aspect of neuronal information processing. The detailed mechanisms that modulate synaptic inputs determine the computational properties any given neuron. We study simple model for summation excitatory from synapses and illustrate its use by characterizing some functional postsynaptic neurons. In this regard, we response neurons as defined to two well known no...
In neurons, transport of a subset of mRNAs to subcellular regions and their translation has a role in synaptic plasticity. Recent studies have suggested a control mechanism of this local translation through mRNA compartmentalization or degradation. Here we report that processing bodies (P-bodies), which are involved in mRNA degradation or storage, are transported to dendrites by conventional ki...
Introduction: Synaptic plasticity has been suggested as the primary physiological mechanism underlying memory formation. Many experimental approaches have been used to investigate whether the mechanisms underlying long-term potentiation (LTP) are activated during learning. Nevertheless, little evidence states that hippocampal-dependent learning triggers synaptic plasticity. In this study, we in...
Background: Among the trophic factors in CNS, the role of neurotrophins for their multiple actions is more pronounced. The purpose of this study was to determine the effect of two weeks light aerobic running on protein levels of Brain Derived Neurotrophic Factor (BDNF) and the specific receptor of TrkB, relying on the more transparent role of exercise on synaptic and neurogenerative modificat...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید