BACKGROUND The effect of segment-specific proximal tubular injury on spatio-temporal osteopontin (OPN) distribution was determined in two different nephrotoxic rat models to evaluate its conceivability with a possible role for OPN in acute renal failure (ARF). OPN gene expression was further determined in proximal and distal tubular cells to investigate the origin of increased renal OPN. METH...

This paper examines the indexical function of prosody in the signalling of discourse deixis and anaphora (in particular, contrastive accent versus low pitch and weak stress on certain types of context-bound referring expressions: demonstrative-based as well as 3rd person pronouns – mainly in English). The choice of contrastive versus weak stress on given expression types of this character will ...

The use of hand gestures to point at objects and individuals, or to navigate through landmarks on a virtually created map is ubiquitous in faceto-face conversation. We take this observation as a starting point, and we demonstrate that deictic gestures can be analysed on a par with speech by using standard methods from constraint-based grammars such as HPSG. In particular, we use the form of the...

This paper examines demonstrative pronouns used as deictics to refer to the interpretation of one or more clauses. Although this usage is frowned upon in style manuals such as (Strnnk and White, 1959), who say "This. The pronoun this, referring to the complete sense of a preceding sentence or clause, cannot always carry the load and so may produce an imprecise statement." it is nevertheless ver...

Temporal lobe epilepsy is characterized by recurrent seizures in one or both temporal lobes of the brain; some in vitro models show that epileptiform discharges initiate in entorhinal layer V neurons and then spread into other areas of the temporal lobe. We previously found that, in the presence of GABAA receptor antagonists, stimulation of afferent fibers, terminating both at proximal and dist...

  Background: Considering the importance of an early diagnosis and proper decision-making in regards to the treatment of pediatric distal radius and elbow fractures, this study examines emergency medicine specialists’ accuracy in the diagnosis and treatment of these patients. Methods: From 2012 and 2013, children less than 14 years old who were referred to an academic hospital emergency departm...