Background: Liposomes constitute a promising drug delivery vehicle, and are believed to improve drugs’ effectiveness. This study was aimed to compare antihypertensive and vascular modifying activities of liposomal and non-liposomal forms of ascorbic acid. Methods: Forty-nine male Sprague-Dawley rats were randomly divided into seven groups (n=7): A sham vehicle-receiving (Sham-veh), hypert...

[1] D. A. Zogas and G. K. Karagiannidis, “Infinite-series representations associated with the bivariate Rician distribution and their applications,” IEEE Trans. Commun., vol. 53, no. 11, pp. 1790–1794, Nov. 2005. [2] A. A. Abu-Dayya and N. C. Beaulieu, “Switched diversity on microcellular Ricean channels,” IEEE Trans. Veh. Technol., vol. 43, no. 6, pp. 970–976, Nov. 1994. [3] K. S. Miller, Mult...

Daniel Janssen, Christian Derst, Jean-Michel Rigo, and Emmy Van Kerkhove 3 4 5 1 Centre of environmental sciences, Department of Physiology, Hasselt University and 6 transnationale Universiteit Limburg, Agoralaan, Diepenbeek, 3590, Belgium 7 2 Biomedical research institute, Hasselt University and transnationale Universiteit Limburg, 8 Agoralaan, Diepenbeek, 3590, Belgium 9 3 Institute for Integ...

Daily injections of parathyroid hormone (PTH) are the only FDA-approved anabolic treatment for osteoporosis; however PTH is only clinically approved for treatment periods of up to 24months. To enhance its anabolic effect, combining PTH with anti-resorptive therapy was proposed and expected to maximize the effectiveness of PTH. The current study aimed to elucidate structural mechanisms through w...

Background: Sex dimorphism in the prevalence, onset, development and progression of cardiovascular disease (CVD) is well recognized, but the mechanisms whereby sex hormones which are believed to confer cardioprotection are still not fully understood. Objective: This study more closely delineates the effect of 17β-Estradiol (E2) on the expression and signaling of the cardiac NP and NOS systems, ...

Manganese overexposure (MnOE) can be neurotoxic. In humans this can occur through occupational exposure, air or water contamination, well water, soy milk, and some baby formulas. In children MnOE has been associated with cognitive and behavioral deficits. The effects of MnOE may be modified by factors such as iron status. We hypothesized that developmental MnOE would be exacerbated by iron defi...