II ECOGNITION of the fully-developed megaloblast in deficiency of vitamm B12 or folic acid is not difficult. In the case of the “intermediate megaloblast” or “megaloblastoid” cell, however, identification of megaloblastic changes often becomes more difficult, and more subjective.1 The present study attempts to reduce this subjectivity by demonstrating a unique clockface chromatin pattern along ...

INTRODUCTION Pseudo-Foster Kennedy syndrome is a triad consisting of ipsilateral optic atrophy, contralateral optic disc edema, and ipsilateral anosmia in the absence of an intracranial mass. Vitamin B12 plays an important role in DNA synthesis, and its deficiency causes peripheral neuropathy, myeloneuropathy, and, very rarely, optic neuropathy. CASE PRESENTATION In this study, we describe a ...

OBJECTIVE To describe the prevalence of iron, folate, and B12 deficiencies in Mexican women of reproductive age from the National Health and Nutrition Survey (Ensanut) 2012. MATERIALS AND METHODS Data came from a national probabilistic survey, representative from rural and urban areas, and different age groups. Blood samples were obtained from 4 263, 20 to 49 years old women for serum ferriti...

Sum mary Aim: To evaluate malnutrition, anemia and related deficiency of vitamin B12, iron and folic acid in children with neurological disease and related nutritional problems. Material and Method: In this study, our aim was to investigate anemia and possible reasons such as iron deficiency, folic acid deficiency and vitamin B12 deficiency among patients with nutritional problems who were admi...

Vitamin B12 is one of the essential vitamins affecting various systems of the body. Reports of psychiatric disorders due to its deficiency mostly focus on middle aged and elderly patients. Here we report a case of vitamin B 12 deficiency in a 16-year old, male adolescent who presented with mixed mood disorder symptoms with psychotic features. Chief complaints were "irritability, regressive beha...

OBJECTIVE To study unusual psychiatric manifestation of vitamin B12 deficiency and related issues. METHOD A case study of 52-year-old female and review of relevant literature. RESULTS Complete remission of psychiatric symptoms without recurrence for the next 4 years with vitamin B12 as the only specific therapy instituted. CONCLUSION Importance of B12 estimation and replacement in patient...

Oral vitamin B12 can provide an effective alternative to intramuscular injections, so giving patients a choice and reducing costs in primary care. This study investigated the effectiveness, safety, and acceptability of oral vitamin B12 as replacement therapy in patients with vitamin B12 deficiency in a city general practice population. Forty patients previously maintained on vitamin B12 injecti...

Deficiencies in vitamin B12 and glutathione (GSH) are associated with a number of diseases including type 2 diabetes mellitus. We tested newly diagnosed Indian diabetic patients for correlation between their vitamin B12 and GSH, and found it to be weak. Here we seek to examine the theoretical dependence of GSH on vitamin B12 with a mathematical model of 1-carbon metabolism due to Reed and co-wo...

introduction: online medicare is a method in which parts of a medical process, whether its diagnostics, monitoring or the treatment itself will be completed by using online services. at the first step the students were registered for using the system. they participated in estimating depression scale; anxiety scale and clinical interview by online medical care system.  subsequently, the lab exam...

Pernicious anemia has recently been recognized as a risk factor for osteoporosis and fractures. Although vitamin B12 is important for osteoblast function, the effect of vitamin B12 replacement in states of vitamin B12 deficiency on bone density and fracture incidence is not known. We report 2-year follow-up data from a patient with severe osteoporosis, multiple vertebral compression fractures, ...