For sums of squares formulas of the form (x1 + · · · + xr)(y 1 + · · · + y s) = z 1 + · · · + z t where the zi are bilinear functions of the xi and yi, we have two wellknown lower bounds on the size of t given r and s. One was obtained independently by Hopf and Stiefel, and another by Atyiah. These bounds are given by requiring certain binomial coefficients be divisible by certain powers of 2. ...

OBJECTIVE Evaluate safety and efficacy of mixed amphetamine salts extended release (MAS XR) in adults with attention-deficit/hyperactivity disorder (ADHD). METHODS 10-week interim analysis of the Quality of life, Effectiveness, Safety, and Tolerability (QU.E.S.T.) trial, an ongoing, 30-week, open-label, multicenter investigation of once-daily MAS XR (10-60 mg/day) in adults (>or=18 years of a...

"Forgiveness" - the difference between a drug's postdose duration of action and its prescribed dosing interval - estimates the margin of therapeutic effect following a missed dose. Because this margin presumably decreases as dosing becomes less frequent, QD dosing of an antiepileptic drug (AED) is expected to be less forgiving than more frequent (e.g., BID) dosing of that same AED. However, if ...

We prove that if the initial ideal of a prime ideal is Borel-fixed and the dimension of the quotient ring is less than or equal to two, then given any non-minimal associated prime ideal of the initial ideal it contains another associated prime ideal of dimension one larger. Let R = k[x1, x2, . . . , xr] be a polynomial ring over a field. We will say that an ideal I ⊆ R has the saturated chain p...

s away from the specialization benefit that is surely an important reason for delegated decision making. We also assume that the voter is capable of determining which of the policy options is in his best interest. A natural starting point to address the issues of expertise and voter ignorance would be to include policy uncertainty along the lines of Gilligan and Krehbiel (1987). This would pres...

OBJECTIVE This study examined the efficacy and safety of clonidine hydrochloride extended-release tablets (CLON-XR) in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). METHOD This 8-week, placebo-controlled, fixed-dose trial, including 3 weeks of dose escalation, of patients 6 to 17 years old with ADHD evaluated the efficacy and safety of CLON-XR 0.2 mg/day or CL...

Background: To date, the European Alliance of Associations for Rheumatology (EULAR) guidelines recommend X-ray (XR) as first line imaging in axial Spondyloarthritis (axSpA) and magnetic resonance (MR) if diagnosis cannot be established by XR clinical features. However, much knowledge has been gained recently strengthening applicability MR detection structural lesions raising question, whether i...

The aim of this preliminary investigation was to assess whether human peripheral blood lymphocytes which have been pre-exposed to non-ionizing radiofrequency fields exhibit an adaptive response (AR) by resisting the induction of genetic damage from subsequent exposure to ionizing radiation. Peripheral blood lymphocytes from four healthy donors were stimulated with phytohemagglutinin for 24 h an...

INTRODUCTION The aim of this study was to evaluate the efficacy and safety of quetiapine fumarate extended release (XR) in the treatment of Korean subjects with acute schizophrenia. METHODS This was an 8-week, multi-center, open-label, non-comparative study to evaluate the efficacy and safety of quetiapine fumarate XR at a daily dose of 400-800 mg. Changes in total scores on the Positive and ...