INTRODUCTION Fresh frozen plasma (FFP) is widely used, but few studies have described patterns of plasma use in critical care. We carried out a multicentre study of coagulopathy in intensive care units (ICUs) and here describe overall FFP utilisation in adult critical care, the indications for transfusions, factors indicating the doses used and the effects of FFP use on coagulation. METHODS W...

BACKGROUND Despite limited evidence, fresh frozen plasma (FFP) transfusions are a relatively common neonatal procedure. OBJECTIVES Quantify FFP usage in our unit; determine indications for transfusions and compliance with published guidelines. METHODS Data were retrospectively collected on infants who received FFP from January 2009 to December 2013. RESULTS Admissions totalled 10 912 infa...

Numerous published guidelines encourage appropriate use of fresh frozen plasma (FFP). However, adherence is documented as poor. Therefore, we sought to determine the laboratory effect of FFP administration to patients with an international normalized ratio (INR) less than 1.6 (prothrombin time <1.6 times normal). We found minimally prolonged INRs decreased with treatment of the underlying disea...

The demand for family financial planning (FFP) services is growing dramatically as the financial market grows more complex and people become more aware of the importance of qualified financial guidance. To provide decision support for FFP-related decisions, we formulate a conceptual model for FFP by following Simon's decision-making process model and map our model to the generic FFP process. Th...

We analyzed 40 cases of falsification, fabrication, or plagiarism (FFP), comparing them to other types of wrongdoing in research (n=40) and medicine (n=40). Fifty-one variables were coded from an average of 29 news or investigative reports per case. Financial incentives, oversight failures, and seniority correlate significantly with more serious instances of FFP. However, most environmental var...

We propose a formalization of the COSMIC Full Function Point (COSMIC-FFP) measure for the Real-time Object Oriented Modeling (ROOM) language. COSMIC-FFP is a measure of functional size. It has been proposed by the COSMIC group as an adaptation of the function point measure for real-time systems. The COSMIC-FFP de nition is general and can be applied to any speci cation language. We propose a fo...

As fresh frozen plasma (FFP) loses coagulation factor activity during the production process, FFP therapy may not be feasible to completely replenish coagulation factor concentrations in a clinical setting. The aim of this study was to describe the results of early replacement coagulation factors with FFP in a simplified and idealized in vitro model of dilution. Six ml of whole blood drawn from...

PURPOSE To describe a novel methodology by which to measure the Hirschberg ratio (HR) in infants. The methodology does not require fixation on specific points, and measurements are made while infants look naturally at a display. METHODS The HR is calculated automatically from measurements of the direction of the optical axis, the position of the pupil center, and corneal reflexes in video ima...

BACKGROUND Indications, efficacy, and safety of plasma products are highly debated. We compared the concentrations of haemostatic proteins and cytokines in solvent/detergent-treated plasma (SDP) and fresh-frozen plasma (FFP). METHODS Concentrations of the following parameters were measured in 25 SDP and FFP samples: fibrinogen (FBG), factor (F) II, F V, F VII, F VIII, F IX, F X, F XIII, von W...