نتایج جستجو برای: 074

تعداد نتایج: 593  

Journal: :Verbum Vitae 2022

Recenzja książek: Zdzisław Żywica, Ewangelia według Świętego Mateusza .Rozdziały 1–13. Wstęp, przekład z oryginału, komentarz(Biblia Impulsy. Nowy Testament 1/1; Katowice: Księgarniaśw. Jacka 2019). Ss. 272. PLN 29,90. ISBN 978- 83-8099-074-6 14–28. 1/2; 2020). 288. 978-83-8099-119-4

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2017

ژورنال: مدیریت ورزشی 2015

  هدف از این تحقیق مطالعۀ ابعاد عینی امنیت و نقش سازمان‌های ورزشی در تأمین و توسعۀ آن از دیدگاه گردشگران ورزشی خارجی بود. روش تحقیق از نوع توصیفی–پیمایشی بود. جامعۀ آماری تحقیق گردشگران ورزشی خارجی شرکت‌کننده در رویداد ورزشی بین‌المللی دهۀ فجر (394 نفر) بودند. روش نمونه‌گیری تمام‌شمار بود. در این تحقیق از پرسشنامۀ محقق‌ساخته استفاده شد. پایایی پرسشنامه 83/0= α به‌دست آمد. سطح معناداری (001/0P=)...

2011
Terry L. Erwin George E. Ball

Badister (Badister) amazonussp. n. is described from Perú, Loreto, 1.0 km SW Boca del Rio Samiria, Vigilante Post 1, 130m, "04°40.5'S, 074°18.9'W" its type locality. It is known also from two other localities in Loreto Department, Perú, in both the Varzea and Igapó river systems. This new species is sufficiently different that a new informal higher taxon, the amazonus species complex, is recogn...

Journal: :Journal of the Endocrine Society 2020

Journal: :Cancer research 2012
Nimali P Withana Galia Blum Mansoureh Sameni Clare Slaney Arulselvi Anbalagan Mary B Olive Bradley N Bidwell Laura Edgington Ling Wang Kamiar Moin Bonnie F Sloane Robin L Anderson Matthew S Bogyo Belinda S Parker

Metastasis to bone is a major cause of morbidity in breast cancer patients, emphasizing the importance of identifying molecular drivers of bone metastasis for new therapeutic targets. The endogenous cysteine cathepsin inhibitor stefin A is a suppressor of breast cancer metastasis to bone that is coexpressed with cathepsin B in bone metastases. In this study, we used the immunocompetent 4T1.2 mo...

2008
Beth A. Biller Laird M. Close Elena Masciadri Eric Nielsen Rainer Lenzen Wolfgang Brandner Donald McCarthy Markus Hartung Stephan Kellner Eric Mamajek Thomas Henning Douglas Miller Matthew Kenworthy

We present the results of a survey of 45 young (.250 Myr), close (.50 pc) stars with the Simultaneous Differential Imager (SDI) implemented at the VLT and the MMT for the direct detection of extrasolar planets. As part of the survey, we observed 54 objects total, of which 45 were close, young stars, 2 were somewhat more distant (<150 pc), very young (≤10 Myr) stars, 3 were stars with known radi...

2004
Aleš Premzl Janko Kos

Background. Lysosomal cathepsins B and D have been reported to play a role in various processes leading to progression of malignant disease. In ras-transformed MCF10A neoT cells both enzymes show similar vesicular distribution in perinuclear and peripheral cytoplasmic regions. Results. The co-localization of cathepsins B and D in some vesicles as defined by confocal microscopy supports their co...

Journal: :Blood 2007
Akihiro Fujisawa Naotomo Kambe Megumu Saito Ryuta Nishikomori Hideaki Tanizaki Nobuo Kanazawa Souichi Adachi Toshio Heike Junji Sagara Takashi Suda Tatsutoshi Nakahata Yoshiki Miyachi

Mutations in the cold-induced autoinflammatory syndrome 1 (CIAS1) gene are associated with a spectrum of autoinflammatory diseases, including familial cold autoinflammatory syndrome, Muckle-Wells syndrome, and chronic infantile neurologic, cutaneous, articular syndrome, also known as neonatal-onset multisystem inflammatory disease. CIAS1 encodes cryopyrin, a protein that localizes to the cytoso...

Journal: :Experimental neurology 1999
K Tsuchiya Y Kohda M Yoshida L Zhao T Ueno J Yamashita T Yoshioka E Kominami T Yamashima

This paper is to study the participation of cathepsin in ischemic neuronal death of the monkey hippocampal cornu ammonis (CA) 1 sector and also to clarify whether its selective inhibitor epoxysuccinyl peptides such as CA-074 and E-64c can inhibit the neuronal death or not. In the preceding reports, we demonstrated mu-calpain activation and subsequent rupturing of the lysosomal membrane of posti...

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