CAN J ANESTH 2000 / 47: 10 / pp 1019–1024 Purpose: Ketamine reduces endotoxin-induced production of proinflammatory cytokines, including tumour necrosis factorα (TNF), in several types of inflammatory cells, including monocytes and macrophages. Transcription of the genes that encode production of these proinflammatory cytokines is regulated by nuclear factor-kappa B (NF-6B). Cytoplasmic B prote...

Background. Human herpesvirus 6B (HHV-6B) is the causative agent for exanthema subitum. This virus has been suggested to have neurovirulence based on the in-vivo and in-vitro studies. HHV-6B has been suggested to be associated with mesial temporal sclerosis (MTS) that results in mesial temporal lobe epilepsy. Aims of this study was to elucidate pathogenic role of HHV-6B in patients with MTS. Me...

Both Neisseria meningitidis and Haemophilus influenzae are important isolates recovered in blood cultures from septicemic children. Sodium polyanetholsulfonate is present in most blood culture media and can inhibit the growth of certain bacteria, including N. meningitidis. The addition of gelatin to blood culture media neutralizes this inhibition. The growth of H. influenzae is enhanced by spec...

A prospective study was conducted to evaluate the radiometric detection of group D and viridans streptococci in blood, using three media preparations, Bactec 6A and 6B isotonic media and 8B hypertonic medium. All enterococci tested were detected by the 6A and 6B media. However, the 6A medium failed to detect 76% of the Streptococcus bovis isolates and 57% of the viridans streptococci, whereas a...