نتایج جستجو برای: 6b

تعداد نتایج: 2501  

Journal: :Journal of virology 2014
Huamin Tang Junjie Wang Nora F Mahmoud Yasuko Mori

UNLABELLED Recently, we identified a novel receptor, CD134, which interacts with the human herpesvirus 6B (HHV-6B) glycoprotein (g)H/gL/gQ1/gQ2 complex and plays a key role in the entry of HHV-6B into target cells. However, details of the interaction between the HHV-6B gH/gL/gQ1/gQ2 complex and CD134 were unknown. In this study, we identified a cysteine-rich domain (CRD), CDR2, of CD134 that is...

Journal: :Journal of clinical microbiology 2014
Yuri Kato Masaru Ihira Mami Umeda Yuki Higashimoto Yoshiki Kawamura Masahiro Ohashi Junichi Ishi Tetsushi Yoshikawa

In order to determine whether mixed infections of human herpesvirus 6B (HHV-6B) occur in immunocompetent and immunocompromised individuals, we examined the copy numbers of telomeric repeat sequences (TRS) of clinical isolates. In clinical isolates obtained from patients with exanthem subitum caused by primary HHV-6B infection, PCR products with HHV-6B TRS ranging between 400 and 800 bp were amp...

Journal: :Philologus 1863

Journal: :The Journal of infectious diseases 2001
M Väkeväinen C Eklund J Eskola H Käyhty

Streptococcus pneumoniae serotypes 6B and 6A are important causes of infections, yet only 6B is included in current vaccines. It is, therefore, crucial to evaluate whether functional antibodies are produced against both types after vaccination. Concentration and opsonophagocytic activity (OPA) of antibodies to 6B and 6A polysaccharides were determined in serum samples from infants immunized wit...

2011
Zhongping Xu Yufang Zheng Yufei Zhu Xiangyin Kong Landian Hu

Deubiquitinating enzymes (DUBs) are important regulators of cell proliferation. Here we identified a functional deubiquitinating enzyme, ovarian tumor domain-containing 6B (OTUD-6B). Mutation of the conserved Cys residue abolished its deubiquitinating activity in vitro. Otud-6b expression was induced with cytokine stimulation in both mouse Ba/F3 cells and primary B lymphocytes followed a rapid ...

Journal: :The Plant cell 2007
Shinji Terakura Yoshihisa Ueno Hideaki Tagami Saeko Kitakura Chiyoko Machida Hiroetsu Wabiko Hiroji Aiba Léon Otten Hironaka Tsukagoshi Kenzo Nakamura Yasunori Machida

Protein 6b, encoded by T-DNA from the pathogen Agrobacterium tumefaciens, stimulates the plant hormone-independent division of cells in culture in vitro and induces aberrant cell growth and the ectopic expression of various genes, including genes related to cell division and meristem-related class 1 KNOX homeobox genes, in 6b-expressing transgenic Arabidopsis thaliana and Nicotiana tabacum plan...

2011
Wen Xu Zhaohui Shi Jun Chen Ruifeng Meng Wenci Gong Shanli Zhu Lifang Zhang

Effective adjuvants are needed to design effective vaccines against Chlamydia trachomatis (Ct). The aim of this study was to observe the immune response stimulated by inoculation of a DNA vaccine encoding a fusion protein comprising multiple Ct major outer membrane protein (MOMP) epitopes and human papillomavirus 6b L1 (HPV 6b L1) as the basis for designing a novel DNA vaccine against genital C...

Journal: :Journal of virology 2006
Simon Metz Pedersen Bodil Oster Bettina Bundgaard Per Höllsberg

Human herpesvirus (HHV) 6A induce fusion from without (FFWO), whereas HHV-6B is believed to be ineffective in this process. Here, we demonstrate that HHV-6B induces rapid fusion in both epithelial cells and lymphocytes. The fusion was identified 1 h postinfection, could be inhibited by antibodies to HHV-6B gH and to the cellular receptor CD46, and was dependent on virus titer but independent of...

Journal: :Journal of clinical microbiology 2011
Jae-Hoon Song Jin Yang Baek Kwan Soo Ko

Recently, Streptococcus pneumoniae serotypes 6C and 6D have been identified. It is thought that they emerged by the replacement of wciN(β) in the capsular loci of serotypes 6A and 6B, respectively. However, their evolution has not been unveiled yet. To investigate the evolution of four serotypes of S. pneumoniae serogroup 6, four genes of the capsular polysaccharide synthesis (cps) locus, wchA,...

Journal: :Journal of virology 2011
Akiko Kawabata Hiroko Oyaizu Takahiro Maeki Huamin Tang Koichi Yamanishi Yasuko Mori

Human herpesvirus 6 (HHV-6) is a T cell-tropic betaherpesvirus. HHV-6 can be classified into two variants, HHV-6A and HHV-6B, based on differences in their genetic, antigenic, and growth characteristics and cell tropisms. The function of HHV-6B should be analyzed more in its life cycle, as more than 90% of people have the antibodies for HHV-6B but not HHV-6A. It has been shown that the cellular...

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