UNLABELLED There is no recommendation for the treatment of herpes zoster neuralgia in pregnancy, as it even sometimes needs administration of strong opioids. MAIN OBSERVATION Here, we report a pregnant woman with severe zoster neuralgia who responded favorably to acetaminophen. Due to the drug's safe profile and good efficacy, acetaminophen can be used as an alternative for herpetic neuralgia...

a positive association between acetaminophen intake and allergic diseases has recently been reported in developed countries with impaired oxidant/antioxidant balance and promotion of atopy as proposed underlying mechanisms. the aim of the study was to explore the relationship between acetaminophen intake and asthma, hay fever, and eczema in the republic of macedonia as a country with acetaminop...

In this work liquid-liquid equilibrium for aqueous two phase system composed of polyethylene glycol di-methyl ether and tri-potassium citrate at different medium pH values (6.00, 7.00 and 8.00) and 298.15 K was studied. The obtained results show that two phase area expanded with an increasing of pH values. The performances of the Merchuk and semi-empirical equations were tested in correlating t...

BACKGROUND We investigated acetaminophen use and identify factors contributing to supratherapeutic dosing of acetaminophen in hospitalized patients. METHODS We retrospectively reviewed the electronic health records of adult patients who were admitted to 2 academic tertiary care hospitals (hospital A amd hospital B) from June 1, 2010, to August 31, 2010, and who received acetaminophen during t...

Acetaminophen, phenylephrine and chlorpheniramine are frequently associated in pharmaceutical formulations against the common cold. Their quantification presents several problems. A HPLC method for the simultaneous determination of these compounds in pharmaceutical formulations such as capsules and sachets, including the separation of impurities and excipients has been developed and validated. ...

New stability indicating chromatographic methods have been developed for estimation of Assay and Impurities of Docetaxel in Docetaxel injection for evaluation of pharmaceutical quality. With this method, the process related impurities and degradants are well separated from the peaks due to placebo. The relative retention times and relative response factors of the known impurities have been esta...

background: fatalities from acetaminophen poisoning are common, but they are preventable by timely treatment with n-acetyl cysteine (nac). in many medical centers, nac is prescribed in keeping with the ingested dose of the drug as revealed through medical history. it seems to significantly differ from the real indications of nac administration based on plasma level of acetaminophen. overtreatme...