In the present decade there is more concentration on ageing disease. Some diseases are going to through their symptoms at early stage. The problem with aging disease like cancer, diabetes Alzheimer and Parkinson are if they are going to uncover at advanced stage it is very difficult to cure them totally , instated doctors can able to stop the growth of the disease up that stage where it was un ...

INTRODUCTION We're assisting in last years to an important change in clinical manifestations of Parkinson disease. Nowadays motor symptoms have best treatments if we compare with those existing some decades ago, which in last term, permits other manifestations being the main disabilities in an advanced Parkinson disease. Among these disabilities cognitives are the most severe due to it's preval...

In recent years, there has been increasing recognition of the features of Parkinson disease that are not related to nigrostriatal dopamine deficiency. This review addresses selected clinical, anatomic, pathologic, and biochemical correlates of the early premotor symptoms of Parkinson disease, later nonmotor fluctuations, and advanced dopa-unresponsive motor and nonmotor features. The recognitio...

background: parkinson's disease (pd) is a neurodegenerative disorder impairing motor, verbal and other abilities. visual evoked potential (vep) assessment is a useful method for analysis of visual system and its function. the present study was designed in order to evaluate whether vep changes are associated with pd. m aterials and methods: in the present study, 100 subjects encompassing 40 pati...

background: there is no documented demographical study on iranian parkinson's disease (pd) patients, so this study was conducted to identify demographic information about patients with pd in iran, and to explore demographical differences between pd patients in iran and other countries. methods: we reviewed medical records of 1656 patients diagnosed with pd, who referred from all parts of iran t...

background and objectives: parkinson's disease (pd) is a common neuropathologic disorder that is caused by degeneration of dopaminergic neurons of dense part of nigra. oxidative stress has been found in the pathophysiology of pd. since α-pinene has strong anti-oxidant effects, the purpose of this research was to study its effects on movement disorders and memory and lipid peroxidation in p...

background & aim:parkinson's disease (pd) is a kind of disorder in the nervous system, which is characterized with multiple movement disorders. factors such as oxidative stress are the most important causes for the degeneration of dopaminergic neurons in the substantia nigra and occurrence of parkinson's disease. thus, medications that have antioxidant functions could be an interestin...

BACKGROUND Human retinal pigment epithelial (RPE) cells produce levodopa and can be isolated from postmortem human eye tissue, grown in culture, and implanted into the brain attached to microcarriers. These implants ameliorated the motor deficits in rodent and nonhuman primate models of Parkinson disease. OBJECTIVE To evaluate the safety and efficacy of unilateral implantation of human RPE ce...