abstract   background: to improve the debilitating features of parkinson disease (pd) different medical and surgical approaches are available. subthalamic nucleus deep brain stimulation (stn-dbs) was appeared to be a promising method during last two decades. this study aimed to evaluate early motor outcomes of this procedure in first trial of iranian patients .   methods: thirty-seven consecuti...

after alzheimer disease, parkinson disease (pd) is considered the most common neurodegenerative disease. its prevalence is the same in all area but it is common in males than females. from every 100 persons who are above 60 years old, one of them has pd. also 5-10% of patients are less than 40 years old. this progressive neuroinflammation disease isn’t fatal. in 60% of cases is with depression....

Although physiological function of alpha-synuclein is not yet clearly understood, accumulating evidence strongly suggests it plays a crucial role in the pathogenesis of Parkinson disease. Pathologically, alpha-synuclein is a major component of Lewy bodies, which is the pathological hallmark of Parkinson disease. Alpha-synuclein pathology is observed in the brainstem nuclei, including the dorsal...

  Abstract   Background: To improve the debilitating features of Parkinson disease (PD) different   medical and surgical approaches are available. Subthalamic nucleus deep brain   stimulation (STN-DBS) was appeared to be a promising method during last two   decades. This study aimed to evaluate early motor outcomes of this procedure in first   trial of Iranian patients .   Methods: Thirty-seven...

background: parkinson’s disease (pd) is a progressive neurodegenerative disorder causing motor and non‑motor symptoms. the latter are common and include autonomic dysfunction, cognitive impairment, and sleep difficulties. many of the non‑motor aspects of pd such as sleep disturbance are more common and significantly affect the day‑to‑day activities of patients and their quality of life. the mos...

background: many patients with parkinson diseases are faced with constant attention disorders and evaluation of these disorders in these patients is important. methods : a cross-sectional study was conducted on 80 patients with parkinson disease and 80 healthy iranian people aged 40 to 70. all participants in the two groups of healthy and patients were examined by neurologists and psychiatrists...

background: parkinson's disease as a progressive disorder of the nervous system leads to the disability of postural control system. objectives: in the present study the effects of pilates exercises on functional balance in patients with parkinson's was investigated. materials and methods: this control trial included 30 patients with idiopathic parkinson's disease who were selecte...