high‐throughput chemical genetic screen of chemical compounds from several commercial libraries has revealed that lithocholic bile acid (LCA), and some other bile acids, can slow yeast chronological aging [1]. The robust geroprotective effect of exogenously added LCA is due to its ability to enter chronologically aging yeast cells, be sorted to both mitochondrial membranes and alter mitochondri...

OBJECTIVE Investigate time-related age differences in cognitive functioning without influences of prior test experience. METHODS Cognitive scores were compared in different individuals from the same birth years who were tested in different years, when they were at different ages. These types of quasi-longitudinal comparisons were carried out on data from three large projects: the Seattle Long...

Senescence is a nearly universal feature of multicellular organisms, and understanding why it occurs is a long-standing problem in biology. The two leading theories posit that aging is due to (i) pleiotropic genes with beneficial early-life effects but deleterious late-life effects ("antagonistic pleiotropy") or (ii) mutations with purely deleterious late-life effects ("mutation accumulation")....

Introduction: Narrative therapy is a psychological intervention focusing on remembering and reconstruction of the people's life events in ways that are of benefit to them, and reduce the impact of challenges in their lives. This study was performed to examine the effect of narrative group therapy (NGT) on aging perceptions and death anxiety among older adults.   Methods: Forty-seven subjects,...

deterioration of seed is one of the most important limiting or even hindering factors in its germination. an evaluation and understanding of the factors responsible for/ and enhancing seed deterioration is of paramount importance. the main aim of this study was to determine the effects of seed deterioration on its germination and as well on the activities of antioxidant enzymes in canola culitv...

OBJECTIVE We investigated neuropsychological markers that can be used to discriminate pathological cognitive aging from normal cognitive aging. METHODS We administered frontal lobe function tests including the Wisconsin Card Sorting Test (WCST), digit span test, lexical fluency test, fixed condition design fluency test, and Trail Making Test B (TMT-B) to 92 individuals with pathological cogni...

purpose: to evaluate the effect of age on stereopsis. methods: we evaluated stereoacuity using tno and titmus test after full correction of refractive errors in  87 randomly selected subjects aged 5-80 years. results: there was a significant relashionship between stereopsis and age such that stereoacuity increased with aging (anova, p<0.001). conculsion: stereopsis decreases with aging and ther...

The ASTM D 1037 six-cycle accelerated-aging test for wood-based panel products was analyzed to determine how each successive aging cycle and selected steps in each cycle contribute to panel deterioration. Hardboard, particleboard, flakeboard, waferboard, and oriented strandboard were evaluated. The rate of panel deterioration generally decreased with each successive aging cycle. Four cycles of ...