The development of degenerative diseases has been linked to oxidative stress and mitochondrial dysfunction. Additionally, it demonstrated that the changes caused by crude oil exposure contribute onset diseases. There is little or no information on anti-degeneration properties Allanblackia floribunda. This study was carried out investigate brain tissues exposed effects A. floribunda as a prevent...

This study was conducted to investigate the effect of Alchornea cordifolia leaf meal (ACLM)/Pawpaw leaf meal (PLM) on the haematology of young rabbits aged 12-14 wks. The study involved twenty four (24) young rabbits of both sexes and of mixed breeds randomly allocated to four treatment groups of two replicates per treatment with three rabbits in each replicate. The treatment groups were design...

Effects of chronic administration of aqueous extract of alchornea cordifolia leaf commonly used in the treatment of diarrhoea, cough, gonorrhoea, chest pain and anemia on the kidney of adult wistar rats was investigated. Rats of both sexes (n=20), with an average weight of 200g were randomly assigned into test (n=10) and control (n=10) groups. Rats in the test group were given the aqueous extra...

Ethnopharmacological relevance: The dry leaf of Alchornea cordifolia (AC) is used, in traditional medicine in the S Nigeria, for the preparation of blood tonic, remedies for urinary, respiratory, liver and gas intestinal disorders. Aim of the study: This study investigated the protective property of AC leaf against liver damage in animals with a view to exploring its use for the treatment of he...

Paracetamol (acetaminophen, PCM) is a widely used over-the-counter analgesic and antipyretic drug. Intake of a large dose of PCM may result in severe hepatic necrosis. Oxidative stress is mediated by oxidative capacities of the PCM metabolite (N-acetyl-para-benzo quinoneimine, NAPQI), which covalently binds to proteins and other macromolecules to cause cellular damage. At low doses, NAPQI is ...

paracetamol (acetaminophen, pcm) is a widely used over-the-counter analgesic and antipyretic drug. intake of a large dose of pcm may result in severe hepatic necrosis. oxidative stress is mediated by oxidative capacities of the pcm metabolite (n-acetyl-para-benzo quinoneimine, napqi), which covalently binds to proteins and other macromolecules to cause cellular damage. at low doses, napqi is co...

BACKGROUND Gentiana floribunda was investigated for the possible hypotensive and vasodilator activities in an attempt to rationalize its traditional use in hypertension. METHODS The crude extract of Gentiana floribunda (Gf.Cr) was studied in anaesthetized rats and isolated thoracic aorta tissues. RESULTS Gf.Cr which tested positive for presence of flavonoids, saponins, sterols, tannins and ...

Dioscorea species is a very important food and drug plant. The tubers of the plant are extensively used in food and drug purposes owing to the presence of steroidal constituent's diosgenin in the tubers. In the present study, we report for the first time that the leaves of Dioscorea composita and Dioscorea floribunda grown under the field conditions exhibited the presence of multicellular oil g...

Different studies describe the anti-inflammatory effects of Scrophularia species, a medicinal plant widely used in folk medicine since ancient times. As knowledge regarding the anti-neoplastic properties of this species is rather limited, we investigated the influence of methanol extracts of different Scrophularia species on cell proliferation, ce...