The leaves of Alchornea floribunda and Alchornea cordifolia are used traditionally as topical anti-inflammatory agents. In this study, two highly lipophilic fractions AFLF and ACLF isolated from A. floribunda and A. cordifolia leaves respectively were investigated for topical anti-inflammatory effects using xylene-induced mice ear oedema as a model of inflammation. AFLF and ACLF at 5 mg per ear...

objective: alchornea floribunda leaves are widely used in ethnomedicine for the management of immuno-inflammatory disorders. we investigated the in vivo and in vitro antioxidant activity of the leaf extract, fractions and isolated compounds of a. floribunda.materials and methods: the ethyl acetate fraction of the methanol leaf extract was subjected to several chromatographic separations to isol...

OBJECTIVE Alchornea floribunda leaves are widely used in ethnomedicine for the management of immuno-inflammatory disorders. We investigated the in vivo and in vitro antioxidant activity of the leaf extract, fractions and isolated compounds of A. floribunda. MATERIALS AND METHODS The ethyl acetate fraction of the methanol leaf extract was subjected to several chromatographic separations to iso...

BACKGROUND Cancer cells rapidly acquire resistance leading to treatment failures. In the present study, we have evaluated the cytotoxicity of 17 methanol extracts from 11 Cameroonian medicinal plants against the sensitive leukemia CCRF-CEM cells and the best ones were further tested on a panel of 8 other human cancer cell lines, including various MDR phenotypes as well as against the normal AML...

Objective: Alchornea floribunda leaves are widely used in ethnomedicine for the management of immuno-inflammatory disorders. We investigated the in vivo and in vitro antioxidant activity of the leaf extract, fractions and isolated compounds of A. floribunda.Materials and Methods: The ethyl acetate fraction of the methanol leaf extract was subjected to several chromatographic separations to isol...

A taxonomic study of the genus Alchornea in Antioquia, Colombia, is presented. Fifteen species are included, three which (Alchornea brittonii, A. bogotensis. and discolor) new records for department. morphological characterization, a identification key, full descriptions, geographic distribution notes provided.

BACKGROUND Cancer chemotherapy is still hampered by clinical failures due to multi-drug resistance (MDR) of tumor cells. In the present study, we have investigated the cytotoxicity of 20 methanol extracts from 10 medicinal plants against the sensitive leukemia CCRF-CEM cells. The most cytotoxic extracts were then further tested on a panel of 8 human cancer cell lines, including various MDR phen...

a tree of 10—20 m popularly known as tapiá, tanheiro-defolha redonda, tanheiro, or canela-raposa. It is found in the southern and southwestern regions of Brazil, mainly in the Atlantic pluvial forest. An ethnopharmacologic survey indicated that some species from the genus Alchornea are commonly used for the treatment of gastric diseases. Despite the common use of this species as a medicinal pla...

Purpose: To assess Alchornea cordifolia, a medicinal plant with numerous biological actions and uses in traditional medicine, for possible toxicity in rats. Methods: The probable effect of the ethanol extract of Alchornea cordifolia (250 2000 mg/kg, p.o.) by gavage was evaluated on blood cellular elements and chemistry, as well as on the weight and histology of vital organs of male adult Spraqu...