The self-condensation of alkynals was for the first time implemented under mild organocatalytic conditions and was successfully linked with a domino organocatalytic inverse-electron-demand oxa-Diels-Alder reaction, which led to the development of a facile one-pot method to produce a wide variety of polysubstituted chiral 3,4-dihydropyrans with good to high yields and diastereoselectivities and ...

The direct aldol-type condensation of aldehydes with ethyl diazoacetate catalyzed by the chiral complex of BINOL derivatives-Zr(O(t)Bu)(4) gave beta-hydroxy alpha-diazo carbonyl compounds with moderate enantioselectivities (53-87% ee). [reaction: see text]

The first synthesis of cytotoxic (-)-taiwaniaquinone A and (-)-taiwaniaquinone F has been achieved through the intramolecular aldol condensation of a ketoaldehyde and the oxidative cleavage of an isopropylidene ketal.

An aldol condensation and an Algar-Flynn-Oyamada oxidative cyclization were key steps in the direct synthesis of chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.

Aldol condensation of n -pentanal can lead to pore blocking and hence transport limitations in supported liquid phase (SLP) catalysts. By careful texture optimization this effect be minimized.

Aldol reactions belong to the most frequently used C-C bond forming transformations utilized particularly for the construction of complex structures. The selectivity of these reactions depends on the geometry of the intermediate enolates. Here, we have reacted octyl pentafluoro-λ6-sulfanylacetate with substituted benzaldehydes and acetaldehyde under the conditions of the silicon-mediated Mukaiy...

Various types of aldehydes undergo crossed-Aldol condensation with ketones in the presence of melamine trisulfonic acid (MTSA) under solvent-free conditions. The reported method is mild, efficient and has the advantages such as using heterogeneous catalysis, short reaction times, high yields of the products and the recyclability of the catalyst.

The 4-oxofurofuran lignan, (+)-aptosimon (1), was synthesized from gamma-butyrolactone (9). To construct the two benzylic chiral center of (+)-aptosimon (1), highly erythro selective aldol condensation and stereoconvergent SN1 intramolecular cyclization were used as the key reactions.

various types of aldehydes undergo crossed-aldol condensation with ketones in the presence of melamine trisulfonic acid (mtsa) under solvent-free conditions. the reported method is mild, efficient and has the advantages such as using heterogeneous catalysis, short reaction times, high yields of the products and the recyclability of the catalyst.

Various types of aldehydes undergo crossed-Aldol condensation with ketones in the presence of melamine trisulfonic acid (MTSA) under solvent-free conditions. The reported method is mild, efficient and has the advantages such as using heterogeneous catalysis, short reaction times, high yields of the products and the recyclability of the catalyst.