allergic asthma is a complex and chronic inflammatory airway disease. interleukin-17 is a pro-inflammatory cytokine which plays critical role in the pathogenesis of allergic asthma. it has been reported that β-arrestin2 regulated the development of allergic asthma at a proximal step in the inflammatory cascade. in this study, the influence of β-arrestin2 on interleukin-17 production and express...

Background & Aims: Asthma is a chronic inflammatory disease of the airways which is associated with the triad of cough, wheezing and dyspnea. Allergic asthma is often associated with a personal or family history of allergic diseases and mostly begins at early childhood. Mold is one of the most common irritants of asthma and allergic rhinitis. In the last 20 years there has been 30% increase in ...

allergic rhinitis is a very common disorder that affects children. to determine the national prevalence of allergic rhinitis symptoms in iranian children, we conducted a systematic review and meta-analysis. we conducted a literature search by using the google scholar from 1992 until 2012. the search terms were included: allergic rhinitis, isaac and iran. all the selected studies on children wer...

Background & Objective: Allergies are manifested with a variety of signs and symptoms. In this study, the frequencies of asthma symptoms, allergic rhinitis, eczema, and related factors among 6- to 7-year-old schoolchildren were investigated. Materials & Methods: This cross-sectional study was carried out among schoolchildren of 35 elementary schools of Zanjan by using the International Study o...

many patients with atopic eczema (ae) would “march” to develop allergic rhinitis (ar) and asthma. physicians, patients and their families often do not appreciate the significance of these diseases as co-morbidities of atopy. the aim of this study was to evaluate the prevalence and severity of airway atopies in patients with ae. ar and asthma severity were assessed in consecutive ae patients see...

background: asthma, allergic rhinitis and eczema as a common disorder in childhood, has many epidemiologic variations in different geographic areas. this study aimed at determining the prevalence of pediatric allergic disease in rural area of babol. methods: this analytical-cross sectional study was performed in 2012 by random sampling on 2 groups of children the first group aged 6-7 years (n=1...

Abstract Aims: To investigate the effect of Myrtenol, the active ingredient of Myrtle, on the oxidant and anti-oxidant indices and cytokines in the allergic asthma. Methods: Allergic asthma was induced by ovalbumin (OVA) sensitization and inhalation in four groups of rats; Control, Asthma, Asthma+Dexamethasone and Asthma+Myrtenol. Myrtenol (50mg/kg) or Dexamethasone (2.5mg/kg) was a...