OBJECTIVE To compare the features of paraneoplastic syndrome of inappropriate antidiuretic hormone with those of limbic encephalitis. DESIGN Case study. SETTING Academic medical center. PATIENT A 46-year-old woman with progressive memory impairment, hyponatremia, and seizures. INTERVENTIONS Magnetic resonance imaging of the brain, fluoro-2-deoxyglucose positron emission tomography of th...

A 78-year-old woman presented with acute confusion, short term memory loss and intermittent jerking movements in her right arm. She had a past medical history of pulmonary embolism, anxiety 3-month cognitive decline. Investigations revealed new hyponatraemia (122 mmol/L (136-145)) osmolalities consistent syndrome inappropriate secretion antidiuretic hormone (SIADH). normal CT MRI brain.

Diabetic neuropathy is the most common diabetic complication. Duloxetine, a serotonin noradrenaline reuptake inhibitor (SNRI), is widely used for the treatment of diabetic painful neuropathy (DPN) because of the efficacy and safety profile. Syndrome of inappropriate antidiuretic hormone secretion, which is strongly associated duloxetine, is a rare but occasionally life-threatening adverse effec...

Introduction It has been suggested that the syndrome of inappropriate antidiuretic hormone secretion might occur in Wernicke's encephalopathy (Shalhoub and Antoniou, 1969; Ebels, 1978; Leading Article, 1979). However, the authors are unaware of published evidence for this although Ebels mentions he has such evidence in a patient. A case is reported in which reversal of the syndrome of inappropr...

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of hyponatremia in cancer patients. It is most frequently reported in association with small-cell lung cancer, but has been reported in other cancers as well. Here we report the case of a patient with myelodysplastic syndrome and blast crisis who developed concurrent hyponatremia. The patient failed to respond to...

BACKGROUND Hyponatremia associated with neuroleptic malignant syndrome has thus far been described as a syndrome of inappropriate secretion of antidiuretic hormone. OBJECTIVES To ascertain and describe the role of cerebral salt-wasting syndrome as the cause of hyponatremia in a patient with neuroleptic malignant syndrome. PATIENT A psychotic patient being treated with olanzapine presenting ...

1. Our purpose was to determine why hypouricaemia is more frequently observed than hypouraemia in the syndrome of inappropriate secretion of antidiuretic hormone. We have retrospectively analysed the scores of 35 patients with a chronic form of hyponatraemia related to the syndrome of inappropriate secretion of antidiuretic hormone and studied prospectively six patients. 2. The patients with hi...