Background Financial constraints, social taboos and beliefs in alternative medicine are common reasons for delaying or not considering treatment for hepatitis C in India. The present study was planned to analyze the impact of non-banking interest free loan facility in patients affected with hepatitis C virus (HCV) in North India.   Methods This one year observational, re...

Background and Aims: Hepatitis C virus is one of the viral infections transmitted by blood transfusion. Patients with thalassaemia frequently need blood transfusion and are in danger of HCV infection. In most cases of infection (85%) the virus evades the immune system and establishes a chronic infection that may lead to cirrhosis and liver carcinoma. Liver is the main site of HCV replication ...

Background: Sodium valproate (VPA), an anticonvalsant drug, has been reported to stimulate viral replication.  A combination therapy with VPA and acyclovir (ACV) is used for the treatment of herpesvirus encephalitis, the commonest sporadic encephalitis of viral origin. Objective: To determine a possible interaction between VPA and ACV leading to a modification of antiviral activity of ACV. Meth...

conclusions we discovered a consistent reduction of serum ace levels by two oral antiviral monotherapies, entecavir and telbivudine. serum ace levels were negatively correlated with egfrs in telbivudine treated patients. objectives we aimed to investigate changes in serum protein abundances associated with renal function in response to antiviral treatments. materials and methods primarily, a tr...

Antiviral agents have been hailed to hold considerable promise for the treatment and prevention of emerging viral diseases like H5N1 avian influenza and SARS. However, antiviral drugs are not completely harmless, and the conditions under which individuals are willing to participate in a large-scale antiviral drug treatment program are as yet unknown. We provide population dynamical and game the...

INTRODUCTION Most hepatocellular carcinomas (HCC) develop in a background of underlying liver disease including chronic hepatitis B. However, the effect of antiviral therapy on the long-term outcome of patients with hepatitis B virus (HBV)-related HCC treated with chemoembolization is unclear. This study aimed to evaluate the survival benefits of anti-HBV therapy after chemoembolization for pat...

Famciclovir and valaciclovir were approved for use in the treatment of herpes zoster despite controversy over antiviral therapy in zoster due to high costs and uncertain benefits. To explore these issues, a Markov decision model was developed, and the incremental cost effectiveness of antiviral treatment for herpes zoster was estimated using these agents compared with no antiviral therapy. A th...

The treatment of Bell’s palsy or idiopathic facial paralysis is highly controversial. Much of this contention surrounds the use of specific antiviral medication in this condition. The widely quoted Scottish Bell’s Palsy Study confirmed the efficacy of prednisolone in the recovery of facial function, but suggested that the antiviral acyclovir provided no benefit, whether administered alone or in...

QUESTIONS UNDER STUDY To evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS) in treatment of Herpes zoster (HZ), and prevention of postherpetic neuralgia (PHN) compared with antiviral drugs. PHN is frequent complication of HZ and may last for months, its treatment isn't very successful. Nonpharmacological regimens for treatment of HZ and prevention of PHN haven't be...

INTRODUCTION Herpes zoster and its sequelae can have a serious impact on quality of life, particularly in the elderly. The duration and severity of herpes zoster symptoms can be reduced with antiviral treatment. Early treatment is most effective. AIM To identify how soon after onset of herpes zoster symptoms adults presented to a suburban Dunedin general practice and to describe which patient...