cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. in this study, the effect of chronic administration of sesame (sesamum indicum l) seed feeding was studied on aortic reactivity of streptozotocin (stz)-diabetic rats. male diabetic rats received sesame seed-mixed food at weight ratios of 3% and 6% for 7 weeks, one week after diabetes in...

background and objective: cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. in this study, the effect of chronic administration of tribulus terrestris (tt) feeding was studied on aortic reactivity of streptozotocin (stz)-diabetic rats and some underlying mechanisms were investigated.    materials and methods: male diabetic rats receive...

background: the vascular function of angiotensin ii-type-2 receptors in adults is controversial. we sought their location and function in mouse aortic rings at young and old mice. materials and methods: male c57bl mice (aged 4 and 14 months) were killed by co2. the descending thoracic aorta was cleaned and dissected into rings. aortic rings were mounted in krebs’ solution at 37 °c and then setu...

Cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. In this study, the effect of chronic administration of sesame (Sesamum indicum L) seed feeding was studied on aortic reactivity of streptozotocin (STZ)-diabetic rats. Male diabetic rats received sesame seed-mixed food at weight ratios of 3% and 6% for 7 weeks, one week after diabetes in...

artemisia species, growing in almost all the northern hemisphere, is used in folk medicine of some countries as a remedy for hypertension. since some cardiovascular disorders including hypertension are accompanied with altered responsiveness of vascular alpha-adrenergic receptors, the effect of aqueous artemisia annua extract (100 and 200 mg kg-1) on a1-adrenoceptor agonist-induced contraction ...

abstract background and objective: vascular abnormality and dysfunction plays an important role in the pathogenesis of vascular disease in diabetic state. in this study, we aimed to investigate whether an in vitro exposure of endothelium-intact aortic rings to melissa officinalis (lemon balm, mo) aqueous extract could have a beneficial effect in rats with subchronic diabetes. materials and meth...

Abstract Background and Objective: Vascular abnormality and dysfunction plays an important role in the pathogenesis of vascular disease in diabetic state. In this study, we aimed to investigate whether an in vitro exposure of endothelium-intact aortic rings to Melissa officinalis (lemon balm, MO) aqueous extract could have a beneficial effect in rats with subchronic diabetes. Materials and Meth...

The hypotensive effect of garlic has been well-documented in human subjects and animals. Since endothelial activity regulates vascular reactivity in physiological and pathophysiological conditions, the aim of the present study was to investigate the effect of garlic on endothelium-dependent and independent relaxation of rat aorta for elucidation of mechanism of the garlic anti-hypertensive effe...

The purpose of this study was to define early events during the angiogenic response of the aortic wall to injury. Rat aortic rings produced neovessels in collagen culture but lost this capacity over time. These quiescent rings responded to vascular endothelial growth factor but not to a mixture of macrophage-stimulatory cytokines and chemokines that was angiogenically active on fresh rings. Ana...