Background: Basal cell carcinoma (BCC), the most common form of skin cancer, usually occurs in the sun-exposed areas of the body like head and neck, yet is also seen in unexpected sites. Myriad studies have mentioned a lower limb BCC incidence rate of 1.5-13.5%.Methods: The present retrospective cross-sectional study was conducted on 650 BCC patients, who were referred to the dermatology tumor ...

background: the most frequently mutated tumor suppressor gene found in human cancer is p53. in a normal situation, p53 is activated upon the induction of dna damage to either arrest the cell cycle or to induce apoptosis. however, when mutated, p53 is no longer able to properly accomplish these functions. the aim of this study was to investigate the expression of p53 gene in cases of skin cancer...

background: cutaneous malignancies are common in dermatologic practice. due to their relation to sun exposure the characteristics of these malignancies can differ in various geographic locations. this study intends to determine the characteristics of surgically treated cutaneous malignancies and various surgical modalities that have been applied. methods: this was a retrospective study of patie...

this case report describes a 59-year-old woman with a giant basal cell carcinoma on the face neglected for 11 years. surgical resection of the lesion resulted in a 13 × 11 cm defect. issues regarding the adequately safe surgical margins and the management of the resultant defect through modern wound dressing technologies are discussed. keywords : giant basal cell carcinoma, modern dressing, gel...

Basal cell carcinoma (BCC) is currently the most common cutaneous cancer found in humans. Although it generally shows a relatively benign course (BCCl), some cases show aggressive behavior (BCC2). Until recently, traditional histologic diagnostic criteria have failed to discriminate unequivocally between BCC 1 and BCC2. In this study we selected 50 cases of BCC and categorized them into tw...

normal 0 false false false en-us x-none ar-sa leishmaniasis is a protozoan infection due to organisms of the genus leishmania. the differential diagnosis of cutaneous leishmaniasis includes arthropod bites, basal cell carcinoma (bcc) and other malignancies. bcc is the most common form of skin cancer. we present a case of cutaneous leishmaniasis resistant to standard intralesional glucantime inj...

Background & Objective:Basal cell carcinoma (BCC) is classified into BCC1 or low risk (nodular, superficial type) and BCC2 or high risk (micronodular, morpheaform, infiltrative, and basosquamous types) based on clinical behavior. This study attempts to evaluate immunohistochemical (IHC) findings and clinical features associated with local aggressiveness and recurrence ...

basal cell carcinoma (bcc) is the most common cancer of the skin. definite diagnosis usually requires histological examination but recently it has been suggested that cytological examination of skin smear can be used as an alternative. to evaluate sensitivity and specificity of cytological examination, a total of 125 skin lesions, clinically suspected to be bcc were studied. cytological samples...

the most frequently mutated tumor suppressor gene found in human cancer is p53. in a normal situation, p53 is activated upon the induction of dna damage to either arrest the cell cycle or else induce apoptosis. however, when mutated, p53 is no longer able to properly accomplish these functions. our aim was to investigate p53 protein alteration in cases of basal cell carcinoma (bcc) and compare ...