objective: to study the prevalence and demographic characteristics of mood disorders among iranian adults. method: in this cross-sectional population-based epidemiological study (age > 18) in iran, 25180 individuals were selected through a randomized cluster sampling method for a diagnosis using the schedule for affective disorders and schizophrenia (sads). they were then interviewed at home by...

Bipolar disorders have a long history. Depression and mania are mankind’s oldest known mental disorders, and they were the first mental disorders conceptualised by Hippocrates as a part of medicine. Mania and depression as part of one and the same disease – what we today call bipolar disorder – was first described by the famous Greek physician of the first Century AD, Aretaeus of Cappadocia. Th...

n contrast to the relationship between substance abuse and bipolar disorder, the relationship between bipolar I disorder and anxiety disorders is vastly underexplored, underappreciated, and certainly understudied. This inattention is surprising in light of the fact that anxiety disorders have the highest rate of comorbidity with bipolar disorder , exceeding the comorbidity rate even of substanc...

Background: Mood disorders are the most common psychiatric comorbidities in substance users. Mood disorders and substance use disorders are 2 intertwined processes in which treating one aid in treating the other. Depression and substance use disorder are now regarded as major mental health issues due to their widespread incidence. The study was designed to investigate the prevalence of major ...

OBJECTIVE Offspring of bipolar parents have a genetically increased risk of developing mood disorders. In a longitudinal study, the authors followed a bipolar offspring cohort from adolescence into adulthood to determine the onset, prevalence, and early course of mood disorders and other psychopathology. METHOD The Dutch bipolar offspring cohort is a fixed cohort initiated in 1997 (N=140; age...

BACKGROUND Bipolar disorder has emerged as a risk factor for substance use disorders (alcohol or drug abuse or dependence) in youth; however, the association between bipolar disorder and substance use disorders is complicated by comorbidity with conduct disorder. We used familial risk analysis to disentangle the association between the three disorders. METHODS We compared relatives of four pr...

background: iran is facing an outbreak of methamphetamine-induced disorders and frequent use of these substances in patients with bipolar disorder. using or intoxication of methamphetamine in patients with bipolar i disorder may alter the patient's clinical profile; however there is limited studies about impact of methamphetamine on clinical manifestation of bipolar disorders. this study aimed ...