objective(s) different types of extended spectrum beta-lactamases (esbls) are encountered in the clinical settings worldwide. there are a few studies regarding the prevalence of esbl genes among klebsiella pneumoniae isolates at tehran especially those of blaper and blactx. the aim of this study was to determine the prevalence of blashv, blatem ,blaper and blactx genes among clinical k. pneumon...

Objective(s):blaCTX-Mand blaPER are two genes that encode class A extended-spectrum β-lactamases (ESBLs) and can be responsible for therapeutic problems. This study was carried out to evaluate the molecular properties of these genes in clinical isolates of Enterobacteriaceae by polymerase chain reaction (PCR), restriction digestion and sequencing. Materials and Methods: During six months, start...

Vibrio parahaemolyticus is an important causative agent of gastroenteritis, with the consumption of contaminated seafood being the major transmission route. Resistance to penicillin is common among V. parahaemolyticus strains, whereas cephalosporin resistance remains rare. In an attempt to assess the current prevalence and characteristics of antibiotic resistance of this pathogen in common food...

5 Abstract Aim: To analyse the occurrence of bla genes (blaIMP, blaVIM, blaGIM, blaSIM, blaSPM, blaPER, blaKPC, and blaOXA) responsible for carbapenemresistance, as well as the presence of cephalosporin-resistance genes (blaCTX-M, blaTEM, blaSHV and blaampC ) by polymerase chain reactions (PCRs). Methods: The study was performed on routine samples subjected to culture and antibiotics susceptibi...

Abstract Background Cefiderocol (CFDC), a siderophore cephalosporin, has broad coverage of Gram-negative bacteria and been approved for clinical use in USA Europe. The SIDERO-WT surveillance studies showed that CFDC shows >95% susceptibility against Acinetobacter baumannii. Against many non-susceptible isolates, most which had blaPER gene, the combination avibactam significantly decrease...

In this study, the contributions of different resistance mechanisms in Pseudomonas aeruginosa isolates were investigated among burned patients. The real-time reverse transcription polymerase chain reaction was performed to determine the expression level of mexY, ampC, and oprD for isolates. Also the isolates were typed by multilocus sequence typing (MLST). Seventy-five per cent of clinical isol...

Vol. 7, No. 5, September-October 2001 911 Emerging Infectious Diseases (blaPER-1 and blaVIM-2 ) had been detected separately among clinical isolates, underscores the possibility of the emergence of new threatening combinations of resistance determinants among nosocomial pathogens. In fact, the recruitment of similar resistance determinants within a single P. aeruginosa strain can determine a re...