نتایج جستجو برای: bmp15 gene
تعداد نتایج: 1141493 فیلتر نتایج به سال:
This study was carried out to identify polymorphisms of BMP15, GDF9 and BMPRIB genes in cross- bred of Romanov×shal sheep. For this reason 79 blood samples were collected from a flock in Gonbad kavous city in Golestan province. DNA was extracted using modified salting out method. Polymerase chain reaction was done by specific primers for amplification of two fragments with 141and 153 bp from ...
Background The presence of different missense mutations in sheep breeds have shown that the bone morphogenetic protein receptor 1B (BMPR1B), bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) genes play a vital role in ovulation rate and prolificacy in ewes. Therefore, the present study aims to investigate BMPR1B, BMP15 and GDF9 gene mutations in prolific ewes of I...
Objective The presence of different missense mutations in sheep breeds have shown that the bone morphogenetic protein receptor 1B (BMPR1B), bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) genes play a vital role in ovulation rate and prolificacy in ewes. Therefore, the present study investigates BMPR1B, BMP15 and GDF9 genes mutations in prolific ewes of Iranian ...
the raini cashmere goat is one of the iranian goat breeds with a high economic value on international markets due to its high production and high quality. the bmp15 gene regulates granulose cell proliferation and differentiation by promoting granulosa cell mitosis, suppressing follicle-stimulating hormone receptor expression, and stimulating the kit ligand expression. this gene plays a pivotal ...
We have taken advantage of the sequence relationships among the bone morphogenetic proteins (BMPs) to identify the mouse Bmp15 and human BMP15 genes. The 392-amino acid prepropeptides encoded by these BMP genes exhibit significant homology to each other, although the 70% identity observed between the 125-amino acid mature peptides is considerably lower than that seen in comparisons of other mou...
Developmental competence of in vitro matured (IVM) oocytes needs to be improved and this can potentially be achieved by adding recombinant bone morphogenetic protein 15 (BMP15) or growth differentiation factor (GDF9) to IVM. The aim of this study was to determine the effect of a purified pro-mature complex form of recombinant human BMP15 versus the commercially available bioactive forms of BMP1...
52 Exogenous oocyte secreted factors such as bone morphogenetic protein 15 (BMP15), together 53 with hormones traditionally used during in vitro oocyte maturation, increase the developmental 54 competence of cumulus oocyte complexes (COCs). Separately, FSH and BMP15 induce 55 different metabolic profiles within COCs, namely FSH increases glycolysis while BMP15 56 stimulates FAD and NAD(P)H auto...
background: bone morphogenetic protein 15 (bmp15) is a growth factor derived from oocyte and is essential for in vivo ovarian follicular growth and in this study, its effects on the improvement of growth and development of follicles during in vitro culture of neonatal mouse ovaries was investigated. methods: two week old mice were cultured for 7 days in the basic culture media with or without f...
The TGF-β superfamily is the largest family of secreted proteins in mammals, and members of the TGF-β family are involved in most developmental and physiological processes. Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), oocyte-secreted paralogs of the TGF-β superfamily, have been shown genetically to control ovarian physiology. Although previous studies found ...
BMP15 and GDF9 are two oogenesis specific genes play a pivotal role in female fertility in mammals and potential for improvement of prolificacy in marker-assisted selection. The aim of present research was to investigate the variation and association between BMP15 and GDF9 polymorphism and litter size in Markhoz goats. The sequence variability of the different amplified fragments utilized for g...
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