Introduction: A relationship between epileptic seizures and brain tissue oxidative damage has been suggested. Ocimum basilicum (O. basilicum) has been shown to have beneficial effects including hypnotic and protective against tissue oxidative damage. The present study was designed to evaluate the effects of O. basilicum hydro-alcoholic extract on oxidative damage of brain tissue following s...

Cardiac diseases are common post-stroke and are associated with increased morbidity and mortality. One possible mechanism of acute cardiac injury is the neurogenic myocardial damage, where the cerebral injury is disturbing the normal sympathetic and parasympathetic neuronal outflow to the heart leading to cardiac damage including myocardial infarctions. The exact mechanism is not completely und...

Introduction: It has been suggested physical exercise exerts neuroprotection in traumatic brain injury (TBI). However little information is available about the effect of endurance exercise on brain edema, inflammation and oxidant activity in diffuse TBI. Therefore, we investigated the prophylaxis effect of endurance training against oxidative damage, inflammation and brain edema assoc...

introduction: the role of brain tissues oxidative damage in learning and memory impairments has been well documented. it is also well known that thyroid hormones have a critical role for the brain functions. the purpose of this study was to investigate the role of brain tissues oxidative damage as a possible mechanism of deleterious effects of propylthiouracil (ptu) - induced hypothyroidism on ...

Traumatic brain injury is considered as one of the main causes of morbidity and mortality worldwide. Apart from primary mechanical injury, Secondary injuries due to inflammation and apoptosis result in great neuronal damage. Current treatments are not able to regenerate the damaged part and prevent future sequels. Using human stem cells with self-assembling scaffolds may be promising in treatme...

catecholamine is a group of neurotransmitters that is believed to be responsible for the normal function of animal brain. physiological and behavioral changes of human body have been reported due to the damage of the brain function following lead exposure. due to the assumption of lead disposal in brain tissue with two year for its half-life, which results in alteration of brain function, we in...