A series of [Pd2L4] coordination cages featuring endohedral functionalities in central backbone positions was synthesized. Although attached via C[double bond, length as m-dash]C double bonds, the substituents behave as molecular rotors. This is explained by their pronounced donor-acceptor character which lowers rotational barriers and allows for electronic control over the spinning rates insid...

The sizes of available self-assembled hydrogen-bond-based supramolecular capsules and cages are rather limited. largest systems have volumes approximately 1400–2300 Å3. Herein, we report a large, hexameric cage based on intermolecular amide–amide dimerization. unusual structure with openings, reminiscent covalently linked cages, is held together by 24 hydrogen bonds. With diameter 2.3 nm cavity...

The self-assembly of a new class of coordination cages formed from two tetrapyridyl-substituted cavitands connected through four square-planar palladium or platinum complexes is reported. The shape of the internal cavity resembles an ellipsoid with a calculated volume of 840 A(3). The four lateral portals have a diameter of about 6 A, large enough to allow the fast entrance/egress of counterion...

Metallosupramolecular cages of the general formulas [M₂(L)₄][X]₄ can be self-assembled in good yields, where M = Pd, X = NO₃, L = L¹ (1a); M = Pd, X = OTf, L = L¹ (1b); M = Pt, X = OTf, L = L¹ (2); M = Pd, X = OTf, L = L² (3); L¹ = 1,3-bis(pyridin-3-ylethynyl)-5-methoxybenzene; and L² = 2,6-(pyridin-3-ylethynyl)- 4-methoxyaniline, respectively. These cages have been fully characterized using ¹H...

The anthracycline antibiotic drug daunomycin has been coupled to fatty acids through formation of a peptide bond with the amino group of its lyxose residue. The arachidonic (C20:4) and docosahexaenoic (C22:6) acid derivatives showed potent in vitro and in vivo cytotoxic activity against rat hepatoma cells producing alpha-fetoprotein. With the exception of the acetate derivative, the complexes w...

In this study, we have employed graphene oxide as a matrix to simultaneously and directly quantify serum nonesterified and esterified fatty acids (FAs) using matrix-assisted laser/desorption ionization-Fourier transform ion cyclotron resonance mass spectrometry (MALDI-FTICR MS). Twelve serum nonesterified FAs combined with their individual esterified FAs (i.e., C16:0, C16:1, C18:0, C18:1, C18:2...

The possible formation of a “cluster molecule” (C20)2 from two single C20 fullerenes is studied by the tight-binding method. Several (C20)2 isomers in which C20 fullerenes are bound by strong covalent forces and retain their identity are found; actually, these C20 fullerenes play the role of “atoms” in the “cluster molecule”. The so-called open-[2+2] isomer has a minimum energy. Its formation p...