Unter dem Begriff der kutanen T-Zell-Lymphome (CTCL) wird eine Gruppe lymphoproliferativer Erkrankungen zusammengefasst, die durch Lokalisation neoplastischer T-Lymphozyten in Haut gekennzeichnet sind. Die Mycosis fungoides (MF) ist häufigste Form von CTCL; sie macht ∼60 % aller primären Lymphome aus. Neben klassischen MF sind zahlreiche klinische und histopathologische Varianten beschrieben wo...

behcet disease (bd) is a systemic inflammatory disease of the unknown etiology. there is however, some evidence to suggest that immunological abnormalities are important in its pathogenesis, furthermore several t-cell abnormalities which may be quite relevant to autoimmune origin of the disease have been described. we report here our study of t-cell subsets, b and nk cells in 68 patients with b...

Background: Regulatory T cells have been suggested to have a protective role against acute rejection in allograft recipients. However, there is little information available about their contribution to chronic rejection process. The role of transforming growth factor-beta 1 (TGF- β1) as a profibrogenic and/or immunoregulatory cytokine in renal allografts is also controversial. Objectives: To eva...

background lichen planus is a disease with unknown etiology that affects the skin and the mucous membranes. immune dysregulation in the pathogenesis of oral lichen planus (olp) is well-known phenomenon. objectives in this study, we compared the levels of the peripheral blood t lymphocytes between patients with olp and control group. patients and methods in this study, 32 and 16 patients respect...

Background: Lymphocyte subsets enumeration is considered prominent in the management of primary and acquired immunodeficiency disorders. Because of local variations due to race, age, gender, and environmental conditions on lymphocyte subsets, and to improve the accuracy of interpretation of laboratory findings, reference intervals must be determined in every population. Objective: To establish ...