BACKGROUND Non-celiac gluten sensitivity is a syndrome characterized by gastrointestinal and extra-intestinal symptoms occurring in a few hours/days after gluten and/or other wheat protein ingestion and rapidly improving after exclusion of potential dietary triggers. There are no established laboratory markers for non-celiac gluten sensitivity, although a high prevalence of first generation ant...

Gluten-related diseases were recently classified into three groups according to their physiopathological mechanisms: autoimmunity (celiac disease, dermatitis herpetiformis, gluten ataxia), allergy (wheat allergyrespiratory, alimentary, contact urticary and WDEIA) and no-autoimmune no-allergic (gluten sensitivity)(30). Dermatitis herpetiformis (DH) is an autoimmune blistering cutaneous disease t...

Celiac disease is an autoimmune disorder of the gastrointestinal tract. It is triggered by exposure to dietary gluten in genetically susceptible individuals. Gluten is a storage protein in wheat, rye, and barley, which are staples in many American diets. Celiac disease is characterized by chronic inflammation of the small intestinal mucosa, which leads to atrophy of the small intestinal villi a...

context celiac disease (cd) is defined as a permanent intolerance to ingested gluten. the intolerance to gluten results in immune-mediated damage of small intestine mucosa manifested by villous atrophy and crypt hyperplasia. these abnormalities resolve with initiationa gluten-free diet. evidence acquisition pubmed, ovid, and google were searched for full text articles published between 1963 and...

Non-celiac gluten sensitivity is defined as a reaction to gluten in persons with a confirmed absence of allergic or autoimmune mechanisms after appropriate laboratory testing. Symptoms resemble those of irritable bowel syndrome (IBS), and may overlap with celiac disease or true wheat allergy. In a research environment, symptoms of non-celiac gluten sensitivity resolve when dietary modifications...

Gluten is a prolamin (gluten protein) found primarily in wheat that has been associated with celiac disease. What is relatively unknown to the general population about gluten is that a certain component of gluten, gliadin appears to be the primary cause of celiac disease. Gliadin is a peptide contained within glutencontaining foods and, upon ingestion, causes inflammation due to stimulation of ...

Celiac disease is an autoimmune enteropathy caused by gluten in genetically predisposed individuals. In celiac disease, adaptive and innate immune activation results in intestinal damage and a wide range of clinical manifestations. In the past, celiac disease was thought to result in signs and symptoms solely related to the gastrointestinal tract. Now, more than half of the adult population pre...

The publication of papers on the topic of gluten related disorders has substantially increased over the last few years. This has motivated healthcare professionals to pay attention not only to celiac disease and wheat allergy but also to a condition termed nonceliac gluten sensitivity (NCGS). Until now this condition has been diagnosed clinically on the basis of exclusion criteria and clinical ...

AIM To investigate whether duration of breastfeeding and timing of gluten introduction influence the age at diagnosis and severity of celiac disease. METHODS Medical records of 89 infants (59 girls and 30 boys; mean age of 14.2 months, standard deviation 4.80) diagnosed with classic celiac disease at the University Children's Hospital in Belgrade from 2000 to 2008 were retrospectively analyze...

The demand for gluten-free products has increased in recent years, owing to the market trends and an increase in the number of celiac and other gluten sensitivities and wheat allergies. Products that contain gluten are also a major diet for a large portion of the world's population. For this reason, the development of gluten-free products is not only an urgent need for celiac patients but also ...