Even though the pandemic caused by Influenza A(H1N1)pdm09 (pH1N1) infection has been extensively investigated, there are few studies that have examined the impact of viral coinfection on disease severity, and they have yielded conflicting results. In this issue of the Jornal de Pediatria, Scotta et al.1 report on a retrospective study of 120 Brazilian children hospitalized with pH1N1 infection,...

Severe NonProliferative Diabetic Retinopathy Any of the following: € Extensive (>20) intraretinal hemorrhages in each of 4 quadrants € Definite venous beading in 2+ quadrants € Prominent IRMA in 1+ quadrant € And no signs of proliferative retinopathy 53A-E: severe to very severe NPDR, 4:2:1 rule One year risk for early PDR: 50.2% (severe NPDR) One year High Risk PDR: 14.6% (severe NPDR) – 45.0%...

BACKGROUND Existing grading systems for acute systemic hypersensitivity reactions vary considerably, have a number of deficiencies, and lack a consistent definition of anaphylaxis. OBJECTIVE The aims of this study were to develop a simple grading system and definition of anaphylaxis and to identify predictors of reaction severity. METHODS Case records from 1149 systemic hypersensitivity rea...

The ability to predict the phenotype of an individual with sickle cell anaemia would allow a reliable prognosis and could guide therapeutic decision making. Some risk factors for individual disease complications are known but are insufficiently precise to use for prognostic purposes; predicting the global disease severity is not yet possible. Genetic association studies, which attempt to link g...

background: the clinical course of multiple sclerosis (ms) evolves over many years. its prognosis is highly variable among affected individuals, i.e. while some suffer from early severe disabilities, others remain ambulatory and functional for many years. we used multiple sclerosis severity score (msss) and the new classification for ms severity herbert et al. introduced in 2006 according to ms...

asthma is now recognized as a common cause of disability of great economic cost and preventable deaths. in this study we aimed to test our hypothesis based on the relationship between body mass index and bronchial asthma .among the patients with acute asthma admitted to the emergency ward and pulmonology clinic, we sought to determine the prevalence of obesity, as well as the effect of body mas...