background: there are many parameters that modulate the severity of sickle cell anemia. fetal hemoglobin (hb f) is one of these major variables. however, its effect is clinically inconsistent. we conducted a descriptive study to assess the influence of hb f on clinical events and hematological variables in patients with sickle cell anemia. methods: 151 patients with sickle cell anemia with a st...

background: in clinical trials of irritable bowel syndrome (ibs), evaluation of treatment efficacy is still mainly subjective.we compared three outcome measures in reflecting response to treatment in a clinical trial of ibs. â  materials and methods: sixty three adult ibs patients participated in a placebo-controlled trial of 10-wk cognitive-behavioral therapy. patients completed the ibs-qualit...

BACKGROUND Parthenium dermatitis is the most common type of airborne contact dermatitis in India. It is a chronic disease of a remitting and relapsing course with significant morbidity and distress, but there is no scoring system to assess its severity. AIM To design a scoring system for the assessment of clinical severity of disease in Parthenium dermatitis and to use this scoring system in ...

Background: In order to describe the patients and evaluate the effectiveness of treatments for widow spider envenomation, investigators require a reliable assessment tool. In this paper, the development of a clinical index for measuring the widow spider bite severity, Latrodectus Envenomation Severity Score (LESS), is described. Methods: According to the valid methods for index development, a D...

background: in order to describe the patients and evaluate the effectiveness of treatments for widow spider envenomation, investigators require a reliable assessment tool. in this paper, the development of a clinical index for measuring the widow spider bite severity, latrodectus envenomation severity score (less), is described. methods: according to the valid methods for index development, a d...

the aim of this study was to assess the role of hla-b*27 and it’s subtypes in determining severity and clinical manifestations of ankylosing spondylitis (as). a total of 163 as patients were assessed for clinical manifestations and severity using structured questionnaires. hla-b*27 screening and b*27 sub-typing were performed by pcr. one hundred twenty two patients (74.8%) were b*27 positive. t...