UNLABELLED We report the case of a 52-year-old woman who developed bilateral anterior and posterior subcapsular cataracts with anterior capsule fibrosis 12 years after exposure to intensive radiation therapy. The woman had uneventful cataract surgery and gained 20/20 corrected distance visual acuity in both eyes. Hematoxylin-eosin staining of the anterior capsule revealed significant subcapsula...

373 Session editor: Alfredo José Mansur ([email protected]) Associate editors: Desiderio Favarato ([email protected]) Vera Demarchi Aiello ([email protected]) Mailing address: Alfredo José Mansur InCor Av. Dr. Enéas C. Aguiar, 44 05403-000 São Paulo, SP, Brazil English version by Stela Maris C. e Gandour Case 5/2001 – Heart failure and insufficiency of the aortic and mitral valves...

Angiosarcoma arising in association with an arteriovenous graft (AVG) or fistula is a unique clinicopathologic scenario that appears to be gaining recognition in the literature. Among reported cases, none has described high-level MYC gene amplification, a genetic aberration that is increasingly unifying the various clinicopathologic subdivisions of angiosarcoma. We therefore report the MYC gene...

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INTRODUCTION Osteopontin (OPN), a multifunctional phosphoprotein, has been implicated in a series of important physiologic and pathophysiologic processes. In breast cancer, OPN functionally contributes to the tumorigenicity of spheroid-forming cells. It also plays a critical role in enhancing the proliferation, tumorigenicity, and ability to display vasculogenic mimicry (VM) of spheroid-forming...

BACKGROUND P53 protein expression has been detected immunohistochemically in papillary thyroid carcinoma(PTC). We investigated the relations between its expression and clinicopathologic features and its significance as a diagnostic marker. MATERIALS AND METHODS We compared and evaluated 93 patients in whom thyroidectomy with lymph node dissection had been performed to treat PTC for clinicopat...

HYPOTHESIS Microsatellite instability (MSI) correlates with clinicopathologic characteristics and long-term prognosis in patients having gastric carcinoma. DESIGN Analysis of prospectively collected data and biologic material. SETTING Tertiary University Hospital, Policlinico "Le Scotte," Siena, Italy. PATIENTS Two hundred fifty patients with gastric carcinoma. MAIN OUTCOME MEASURES Fiv...

The clinicopathologic features of thyroglossal duct cyst when it develops ectopically in the thyroid gland remain unclear because its rarity, which makes diagnosis difficult. Clinical and treatment should not disregard possibility cysts located gland. We here report current case to prepare others provide data for this kind disease.