a rare case of splenic harmartoma in a 31 year old female is reported. she was admitted with splenomegaly, fever and chronic history of epistaxis. routine hematological survey revealed pancytopenia and mild hypercellular marrow. abdominal sonography showed a space-occupying lesion in the spleen which was suspected as malignant tumor. splenectomy was performed and histologic findings were diagno...

primary adrenal lymphoma is extremely rare. we report a case with primary bilateral adrenal lym-phoma in a young male patient. he presented with abdominal pain and weight loss. pathologic study revealed malignant lymphoma, diffuse large cell type (t- cell origin). patient recieved combination chemotherapy and radiation therapy but 22 months after diagnosis died because of progression of dis ease

conclusions imp3 immunoreactivity was associated with poor differentiation of tumor yet not associated with tumor size depth of invasion or lymph node involvement. results immunoreactivity pattern of imp3 was cytoplasmic in different clinicopathologic findings. among different clinicopathologic findings, we found a statistical relationship between tumor differentiation and imp3 (p = 0.047); so ...

background: microsatellite instability (msi) is a mutational signature that is the hallmark of lynch syndrome, and msi testing is a cost-effective method to screen the disease. since there is no enough data about msi status and associated clinicopathologic features of hereditary nonpolyposis colorectal cancer (hnpcc) in iran, our study is a new trial to describe them in center of iran (isfahan)...

abstract background: gastric cancer is one of the most common cancers in the world especially in iran. there are many genomic and molecular factors that cause gastric cancer to occur. also, many markers that associate with tumor invasiveness have been known.  e-cadherin is a calcium- mediated cell adhesion molecule. in some studies, abnormal expression of e-cadherin has been seen in gastric car...

A case of vaginally delivered stillborn female thoracopagus conjoined twins is presented. Each twlin had a cleft lip and cleft palate. They shared a common pericardial sac and a common abdominal cavity. The liver was conjoined, and the small bowel was common to both twins. One twin was asplenic. Although the twins were monozygotic, their viscera were neither identical nor mirror-image to each o...

Background: Precancerous lesions are disorders that are highlylikely to become malignant. Early diagnosis of precancerous skinlesions helps to prevent skin cancers. The aim of this study wasclinicopathological assessment of precancerous skin lesions inpatients referred to the dermatology department of Imam Rezahospital.Method: Two hundred and nine patients who were diagnosed withprecancerous le...