background: the aim of this study was to assess epidemiology of colorectal cancer (crc) in isfahan, iran. materials and methods: data were gathered from hospital documents of hospital admissions for colonoscopy, surgery, chemotherapy or radiotherapy due to colorectal cancer during 1996-2003. results: 1100 cases with colorectal cancer in seven years were detected and reviewed. our minimum incide...

Colorectal cancer (CRC) is the third leading cause of cancer-related death worldwide, and its occurrence can be ascribed to genetic susceptibility. Mitochondrial DNA 4977-bp (mtDNA 4977), as the most described mtDNA deletion, has been long proposed to be involved in various types of cancers. However, a few studies on mtDNA 4977-bp deletion in Iranian patients with CRC have been reported. The cu...

aim : we aimed to explore the frequency of braf v600e mutation in iranian patients with colorectal cancer (crc) as well as its association with clinic pathological characteristic of patients.   background : crc is the third leading cause of cancer related death. there is a growing body of data showing the association of braf v600e mutation with malignant transformation and clinical outcome of d...

abstract introduction: in recent years, many studies employed and found an association between type 2 diabetes mellitus and colorectal cancer. although increased risk of colorectal cancer in individuals with non insulin dependent diabetes mellitus (niddm) has been observed in previous studies, limited information is available on the colorectal cancer associated with niddm in iran. the purpose o...

Background: Cancer-associated fibroblasts (CAFs) are notably involved in colorectal cancer (CRC) tumorigenesis, progression, and treatment failure. In this article, we report the silico development of a CAF-related prognostic signature for CRC.

Background: Colorectal Cancer (CRC) is a serious health problem, and its early detection is crucial for treatment and reducing mortality. Beliefs related to colorectal cancer are an affecting factor in a person’s decision about the CRC Program. The current study aimed at assessing the knowledge, attitude, and practice of healthcare providers regarding colorectal cancer screening based on the He...

background while colorectal cancer (crc) is one of the most preventable causes of cancer mortality, it is one of the leading causes of cancer death in canada where crc screening uptake is suboptimal. given the increased rate of mortality and morbidity among mental health patients, their condition could be a potential barrier to crc screening due to greater difficulties in adhering to behaviours...

Ulcerative colitis (UC) is an inflammatory bowel disease that mainly affects young people. Colorectal cancer (CRC) one of the UC complications. This review considers epidemiology, risk factors, diagnosis and screening, drug prevention CRC in UC. Various treatment options for dysplasia associated with are described. Taking into account lack literature to standardize colorectal approaches (especi...