Leptospirosis is a disease with a large geographical spreading. The clinical picture varies from undiagnosed, flulike syndrome to multiorgan involvement forms. Involvement of pericardium during leptospirosis is a rare event but not unknown. Objective: Our aim is to describe a severe case of leptospirosis (Weil's diseases) with prominent liver involvement, complicated with exudative pericarditis...

We reviewed a series of 5 cases of leptospirosis treated in our hospital between 1998 and 2004 and found that lung involvement was observed in 3 of the 5 cases. All patients met the criteria for the diagnosis of leptospirosis. Weil syndrome was diagnosed in 4 patients and anicteric leptospirosis in 1 patient. The 3 patients with lung sequelae were admitted into the intensive care unit because o...

Leptospirosis is a zoonosis of worldwide distribution, spread by the urine of infected animals. It is a major public health problem, especially in developing countries, where circumstances for transmission are most favourable. The clinical picture varies from mild disease to a severe illness with haemostatic derangements and multiorgan failure eventually leading to death. Although the haemorrha...

Leptospirosis is a zoonotic disease that causes severe manifestations such as Weil's disease and pulmonary hemorrhage syndrome. The aim of this study was to evaluate whether reactive oxygen species (ROS) production and antioxidant reduced glutathione (GSH) levels are related to complications in patients hospitalized with leptospirosis. The ROS production and GSH levels were measured in blood sa...

leptospirosis is a zoonotic disease and has a worldwide distribution. the most important source of infection is infected animal and the main way of transmission is water. major epidemics, usually fallowed by heavy rainfall and flood events. the bacterial infection causes complications such as septicemia, interstitial nephritis, hemolytic anemia, and abortion in most of livestock species. the pr...

BACKGROUND Disseminated intravascular coagulation (DIC) is common among patients with sepsis. Leptospirosis is an important cause of sepsis in tropical areas, and pulmonary hemorrhage associated with thrombocytopenia is the major cause of death, but the coagulopathy in severe leptospirosis has not been further characterized. The aim of this study was to evaluate coagulation factors and the pres...