Multicomponent reactions (MCRs) are one of the most important processes for the preparation of highly functionalized organic compounds in modern synthetic chemistry. As shown in this review, they play an important role in organophosphorus chemistry where phosphorus reagents are used as substrates for the synthesis of a wide range of phosphorylated heterocycles. In this article, an overview abou...

Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as they display vast biological activities. Recent efforts concerning preparation oxindole using isatin-based multicomponent reactions (MCRs) constitute a advance generating druglike libraries fast and with wide scaffold diversity. In this review, we address those recent developments, exploring syntheti...

Selenocysteine containing peptoids and peptide-peptoid conjugates were synthesized by combinatorial Ugi-MCRs (multicomponent reactions) in water: for the first time, an acetal (selenoacetal 2a) was used in Ugi-MCR to furnish selenocysteine peptoids in one step as model compounds for selenocysteine peptides and proteins.

We consider production technologies in which several parallel component processes are characterized by both component-specific and shared inputs outputs. The recently developed multicomponent variable constant returns-to-scale (MVRS MCRS) models of such based on the assumption that we have no information about actual allocation outputs to processes, is a common scenario many applications. MVRS ...

two  simple  protocols  for  the  synthesis  of  1,  2,  4,  5-  tetrasubstitutedimidazoles  using  nano-spa  as  a  reusable,  eco-  friendly,  inexpensive,  and  efficient  catalyst  are  reported.  short   reaction  times,  high  yields,  scale-up  and  easy  workup  are  the   advantages of these protocols.

     A very efficient one-pot three-component synthesis of pyran derivatives has been improved by condensation of aldehydes and malononitrile with dimedone under 80 °C using sucrose as natural and biodegradable catalyst in water. This method offers some advantages including inexpensive, high to quantitative yields, short reaction time, and easy work-up. Therefore, this methodology is entirely g...

The multicomponent reactions (MCRs) produce one compound from three or more reactants. Due to the innumerable combination possibilities of reagents, MCRs are popular because their simplicity and versatility. In this research, an one-pot three-components reaction was carried out between 1,3-diethyl barbituric acid, malononitrile, aldehydes in presence Cu/Co/Ni/MWCNTs as a recyclable catalyst. Th...

Title of Dissertation: CHALLENGES AND RESILIENCE IN THE LIVES OF MULTIRACIAL ADULTS: THE DEVELOPMENT AND VALIDATION OF A MEASURE Nazish M. Salahuddin, Doctor of Philosophy, 2008 Directed By: Associate Professor Karen M. O’Brien, Department of Psychology The purpose of the present study was to develop and validate the Multiracial Challenges and Resilience Scale (MCRS). The MCRS is a measure of t...