The biraderi (brotherhood) is a long-established, widely prevalent dimension of social stratification in Pakistani communities worldwide. Alongside consanguinity, it offers a route for cementing social solidarities and so has strong socio-biological significance. A detailed breakdown of biraderi affiliation among participants in an ongoing birth cohort study in the northern English city of Brad...

OBJECTIVE To investigate the influence of consanguineous marriage on male factor infertility in Lebanon, where rates of consanguineous marriage remain high (29.6% among Muslims, 16.5% among Christians). DESIGN Clinic-based, case-control study, using reproductive history, risk factor interview, and laboratory-based semen analysis. SETTING Two IVF clinics in Beirut, Lebanon, during an 8-month...

BACKGROUND AND OBJECTIVES There is a high rate of consanguinity in Saudi Arabia; however, information on its relationship with genetic disorders is limited. The objective of this cross-sectional study was to explore the role of consanguinity in genetic disorders. SUBJECTS AND METHODS The study sample was determined by a multistage probability random sampling procedure. Consanguinity status wa...

more often patients refer for genetic counseling, without definite diagnosis. mostly people and some doctor! have the impression the all muscular dystrophy affected by boys but is carried by girles. more often review of medical history of theses patients resolved this finding different clinical (neurologists), physiotherapist (ncv,emg) and pathologists diagnosis and also negative result molecul...

OBJECTIVE With 20-30% of all marriages occurring between first cousins, increasing attention in Jordan is now given to role of consanguinity in the occurrence of genetic diseases. The objective of this study is to define the specific categories of genetic disorders associated with consanguineous marriages. METHODS Etiological categories and consanguinity rates were studied among 623 families ...

Marriage between biological relatives is widely popular in many parts of the world, with over 1000 million people living in countries where 20-50+% of unions are contracted between couples related as second cousins or closer. Consanguinity is, however, a controversial topic, in part due to public misunderstanding, complicated by often exaggerated past estimates of the adverse health outcomes. W...

Marriage between close biological kin is widely regarded as genetically disadvantageous in contemporary western societies, but consanguineous unions remain preferential in north africa, the Middle east and large parts of asia, with marriage between first cousins particularly popular. Many major populations also are subdivided into endogamous communities that have distinctive breeding pools. it ...

115 couples with consanguineous marriage, who had experienced reported abortions or still births either in their close relatives (3 couples) or themselves (1 couple) were exposed to genetic counseling (at the shahid akbarabadi hospital) cytogenetic studied were carried out using both conventional staining and g.t.g banding for all the cases studied. the investigation demonstrated various forms ...