نتایج جستجو برای: core protein
تعداد نتایج: 1424777 فیلتر نتایج به سال:
conclusions results showed that hcvcp + bcg induced a moderate ctl and mixed th1/th2 immune responses with higher levels of cell proliferation and ifn-γ secretion, indicating that bcg may have a better outcome when formulated in hcvcp-based subunit vaccines. results expression and purification of core protein around the expected size (21 kda) was confirmed by western blotting. the hcvcp + bcg v...
وکتورهای آدنو ویروس همواره در طراحی واکسن برای کنترل ویروس hcv مورد استفاده قرار گرفته اند. با آنکه ژن core ویروس به دلیل شباهت بالا در بین ژنوتیپها در واکسنهای مختلف مورد استفاده قرار گرفته و از لحاظ تئوری از بهترین کاندیدهای واکسن به شمار می آید، دسته ای ازجدیدترین مطالعات به دلیل نقائص وارد بر ژن کامل از قسمتهای کوتاه شده ژن در ساخت واکسن استفاده می کنند. تاکنون مطالعه ای که به ارزیابی سیستم...
Background and Aims: The hepatitis C virus (HCV) F protein is a recently described, frameshift product of HCV core encoding sequence. Its function and antigenic properties are unknown. In order to assess the presence of antibodies specific for F protein we characterized specific anti-F antibodies in patients with chronic HCV infection. Methods: The F protein was cloned from the HCV genome....
The present work was designed to classify and differentiate between the dehalogenase enzyme to non–dehalogenases (other hydrolases) by taking the amino acid propensity at the core, surface and both the parts. The data sets were made on an individual basis by selecting the 3D structures of protein available in the PDB (Protein Data Bank). The prediction of the core amino acid were predicted by I...
بررسی بیان ژنهای دخیل در سیستم دفاعی گندم نسبت به mycosphaerella graminicola با استفاده از cdna-aflp
aflp یک ابزار قدرتمند برای تشخیص رونوشت هایی با فراوانی کم است و می تواند بعنوان یک روش کارآمد برای جداسازی ژنهایی که بطور متمایز بیان می شوند، بکار رود. بنابراین القا متمایز ژنها در گندم ( رقم چمران و مرودشت) در پاسخ به قارچ m.graminicola بوسیله آنالیز cdna-aflp مورد مطالعه قرار گرفت . در ابتدا گیاهان بوسیله بیمارگر مایه زنی شدند. نمونه برداری در 6 نقطه زمانی(0، 12، 24، 48، 72 و 96 ساعت) بعد ا...
The polymerase chain reaction (PCR) was used to amplify a 578 bp fragment of the poxvirus 4b core protein. Avipoxvirus (APV) specific DNA was detected in all 10 different isolates (each of which had been isolated from an epidemic) isolated from chicken; canary and mynah were collected from Tehran province. Sequencing was performed for 2 isolates as representative and the nucleotide sequence sho...
Background: We examine the GA-repeat core promoters of MECOM and GABRA3 in human embryonic kidney-293 cell line and show that those GA-repeats have promoter activity,and those different alleles of the repeats can significantly alter gene expression.We propose a novel role for GA-repeat core promoters to regulate gene expression in the genes involved in development and evolution. Materials and M...
For various reasons, it seems sensible to redesign or design proteins from the inside out. Past approaches in this field have involved iterations of mutagenesis and characterisation to 'evolve' designs. Increasingly, combinatorial approaches are being taken to select 'fit' sequences from libraries of variant proteins. In particular, in silico methods have been used to good effect. More recently...
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