INTRODUCTION Corneal thinning disorders caused by keratoconus often lead to protrusion, irregular astigmatism, and even perforation. Keratoconus, like other corneal ectasia, does not have a known cause. Severe cases of keratoconus may require correction or restoration of tectonic integrity of the cornea by surgical means. Intracorneal ring segments are a new modality in the treatment of corneal...

Keratoconus (KCN) is an ectatic disorder with progressive corneal thinning and a clinical picture of corneal protrusion, progressive irregular astigmatism, corneal fibrosis and visual deterioration. Other ectatic corneal disorders include: post-LASIK ectasia (PLE) and pellucid marginal degeneration (PMD). Corneal crosslinking (CXL) is a procedure whereby riboflavin sensitization with ultraviole...

PURPOSE Lymphatic research has progressed rapidly in recent years. Lymphatic dysfunction has been found in myriad disorders from cancer metastasis to transplant rejection; however, effective treatment for lymphatic disorders is still limited. This study investigates the role of angiopoietin-2 (Ang-2) in corneal inflammatory lymphangiogenesis (LG) in vivo and in lymphatic endothelial cell (LEC) ...

Contact lens-related complications are common, affecting around one third of wearers, although most mild and easily managed. lenses have well-defined anatomical physiological effects on the ocular surface can result in other consequences due to presence a biologically active material. A contact lens interacts with tear film, surface, skin, endogenous environmental microorganisms, components car...

Cover illustration: Coat of arms and location of the two Swedish counties Småland (lat. Smolandia) and Hälsingland (lat. Helsingia or Helsinglandia) wherefrom the two corneal disorders described in this thesis originate. Published articles and figures have been reprinted with the permission of the copyright holders. To my family and in memory of my father Turmoil accompanies every great change....

Ultraviolet B (UVB) irradiation is the most common cause of radiation damage to the eyeball and is a risk factor for human corneal damage. We determined the protective effect of fucoxanthin, which is a carotenoid found in common edible seaweed, on ocular tissues against oxidative UVB-induced corneal injury. The experimental rats were intravenously injected with fucoxanthin at doses of 0.5, 5 mg...

Degenerations are defi ned as the gradual deterioration of a tissue or an organ that was previously normal with frequent loss of functional activity. Corneal degenerations are characterized by the deposition of material, thinning of tissue, and vascularization. Contrary to corneal dystrophies, they are not hereditary and could be unilateral. Moreover, because of the continuous exposure to envir...

The corneal topographer is an indispensable tool and plays a critical role in the practice of refractive surgery. In corneal refractive surgery, corneal topography is used preoperatively to detect irregular astigmatism, ectatic corneal disorders, or other abnormalities, and to monitor topographic stability following discontinuation of contact lens wear. Postoperatively, it is used to monitor an...

Corneal reconstruction is among the most effective methods for curing corneal injury due to various clinical disorders. Mesenchymal stem cells (MSCs) are a type of multipotent cells distributed in various tissues, which can be easily isolated and expanded in vitro. MSCs are self-renewable and have the potential to transdifferentiate into other type of cells under certain conditions. More recent...

normal 0 false false false en-us x-none ar-sa background : the aim of this study was to determine the correlation between corneal hysteresis (ch) and the corneal resistance factor (crf), which are both novel methods of analyzing ocular rigidity/elasticity, and various corneal characteristics, mainly corneal volume in normal subjects. methods : this cross-sectional study included 500 normal eyes...