coronary artery disease (cad) including myocardial infarction (mi) as its complication, is one of the most common heart diseases worldwide and also in iran, with extremely elevated mortality. cad is a multifactorial disorder. twin and family studies at different loci have demonstrated that genetic factors have an important role in the progression of cad. many studies have reported a significant...

background: paraoxonase-1(pon1), a high-density lipoprotein (hdl) associated enzyme, is believed to contribute in the patho­genesis of coronary artery disease (cad). the aim of this study was to evaluate the association of pon1 promoter c (-107)t polymorphism with the extent of coronary artery stenosis in iranian patients. methods : the rflp analysis for determination of the c(-107)t genotype d...

conclusions in total, application of therapeutic approaches in patients with cad depends on many factors. in our study not only risk factors such as gender, lifestyle, smoking, alcohol abuse, diabetes and hypertension were associated with the incidence of cad, but also they were highly correlated with the severity of the disease. results the mean age of total patients was 58.3 ± 11.5 years (p =...

conclusions the eft, as measured by echocardiography, with a cut off value 2.95 mm has a strong association with premature cad. results among baseline characteristics, waist circumference, triglyceride levels, cigarette smoking and history of statin use were significantly higher in the cad group. the body mass index (bmi) was significantly higher in the non-cad group. according to echocardiogra...

  Objective(s): Apolipoprotein E genotype (APOE) polymorphism affects lipid levels and coronary artery disease (CAD) risk. The aim of this study was to study the association of the Apolipoprotein E genotypes with coronary artery disease in the Iranian population.   Materials and Methods: The Apolipoprotein E genotype in DNA samples extracted from 66 CAD+ patients and 61 control s...

background: systolic blood pressure recovery (rsbp) is of prognostic value for predicting the survival and co-morbidity rate in patients with coronary artery disease (cad). this study investigated the association between rsbp and exercise indices after complete cardiac rehabilitation program (cr) in a population-based sample of patients undergoing coronary artery bypass grafting (cabg). methods...

introduction: the aim of this study was to evaluate the impact of measurement of coronary artery calcification score (cac) in patients with suspected coronary artery disease (cad) and a normal myocardial perfusion scan. methods: in a prospective study we measured the calcium score of 74 patients (29 m, 45 f, mean age 58.7 (m) and 64.4 (f)) with suspicion of cad and a normal perfusion scan. in ...

background: more diagnostic techniques require a better understanding of the forces and stresses developed in the wall of the left ventricle. the aim of this study was to differentiate significant coronary artery disease (cad) patients using a non-invasive quantification of myocardial wall stress in the diastole phase. methods: sixty male subjects with sinus rhythm (30 patients with significant...