introduction: heart failure is a major hazard for public health. despite recent advance in medical therapy, there is not enough information on the outcome of off-pump coronary artery bypass (opcab) and medical therapy on the patients with severe ventricular dysfunction and triple-vessel (cad). this study aimed to compare treatment outcomes and mortality rate in patients undergoing off-pump coro...

impaired fasting glucose identifies individuals at high risk of progression to diabetes but the role of ifg as a coronary artery disease risk factor, independent of its progression to diabetes and its association with other coronary artery disease risk factors ,is unclear. a cross-sectional study was conducted to evaluate the hypothesis that impaired fasting glucose increased the likelihood of ...

percutaneous coronary angioplasty (ptca) of a coronary stenosis without documented ischemia at noninvasive stress testing is often performed, but its benefit is unproven. coronary pressure– derived fractional flow reserve (ffr) is an invasive index of stenosis severity defined as the ratio of maximal blood pressure in a stenotic vessel to the normal maximal pressure in the same vessel. ffr is a...

Introduction: Coronary artery disease secondary to atherosclerosis is the most common cause of mortality. Coronary angiography is the most precise method for determining the extent of disease in the coronary vascular bed. Arterial stiffness has been proposed as a marker of atherosclerosis in some studies. One of the noninvasive methods for the determination of arterial stiffness is Doppler echo...

Background: The aim of this study was to assess the relationship between hypertension and aldosterone-renin ratio (ARR) with the severity of coronary artery disease (CAD). Methods: This cross-sectional study was performed on non-diabetic patients who were candidate for coronary angiography in Shafa hospital in Kerman in 2017. The levels of active renin and ald...

Background: Plasminogen activator inhibitor-1 (PAI-1) is a glycoprotein with inhibitory effects on the formation of plasmin from plasminogen by plasminogen activator. Thus, it prevents clot lysis in vessel walls. Several evidences prove the relationship between coronary artery disease and response to fibrinolytic therapy in patients with myocardial infarction with PAI-1 level. Opium addiction i...

the balance between reactive oxygen species production and antioxidant activity has an important role in oxidative stress associated diseases including coronary artery disease. in this study, the prooxidant-antioxidant balance (pab) and its correlations with serum lipid levels, uric acid levels, and severity of coronary artery involvement were examined. the aim of this study was to determine th...

Background and Objectives: In spite of large number of studies conducted so far, sudden cardiac death remains an enigma and relative importance of acute coronary events as a trigger of sudden death is currently unclear. An autopsy study of heart was therefore planned to observe various histomorphological cardiac changes, and to determine the frequency association of acute coronary events and my...

background and objectives: in spite of large number of studies conducted so far, sudden cardiac death remains an enigma and relative importance of acute coronary events as a trigger of sudden death is currently unclear. an autopsy study of heart was therefore planned to observe various histomorphological cardiac changes, and to determine the frequency association of acute coronary events and my...