Antibodies against Echinococcus multilocularis metacestodes were screened by immunoblotting sera from patients with alveolar echinococcosis (n = 39), cystic echinococcosis (n = 109), or other parasitic infections (n = 66) and healthy individuals (n = 32). Two antigens, approximately 70 and 90 kDa, are found to be valuable for confirmatory diagnosis, with a sensitivity and specificity of 100 and...

The distribution of four antigens of alimentary tract origin was studied in meconium collected from healthy and cystic fibrosis (CF) neonates. Two antigens, carcinoembryonic antigen and a beta glycoprotein designated Mec 6, had significantly lower concentrations in the meconium from CF neonates compared with that from healthy full-term infants. As their concentrations were unrelated to whether ...

BACKGROUND Aspergillus fumigatus, a widely distributed fungus, has been implicated in causing life threatening infections as well as severe asthma and allergic diseases in man. Allergic affliction like allergic bronchopulmonary aspergillosis (ABPA) is a disabling lung disease frequently seen in patients with asthma and cystic fibrosis. Immunodiagnosis of the former is comparatively easier due t...

An increasing number of cases of echinococcosis in Thailand have been imported, probably native infections and medical transfers. Serodiagnosis is one diagnostic choice for interpreting infections before a further step is done. Due to limited antigen, indirect ELISA has been used as a negative screening test for IgG-detection to rule out echinococcosis. Native hydatid cystic fluid (HCF) antigen...

PURPOSE Human alveolar (AE) and cystic echinococcosis (CE) caused by the metacestode stages of Echinococcus multilocularis and E. granulosus, respectively, lack pathognomonic clinical signs. Diagnosis therefore relies on the results of imaging and serological studies. The primary goal of this study was to evaluate the efficacy of several easy-to-produce crude or partially purified E. granulosus...

To confirm the diagnosis of diffuse cystic angiomatosis, it is necessary to biopsy the bone: the walls of the cysts react to immunological markers of the endothelium (antigens related to factor VIII and CD31). Alternatively, lymphography can avoid the necessity for biopsy. Evolution of the condition is variable and depends on the extent of visceral involvement, and usually the extent of soft ti...