Solid-phase extraction method followed by direct UV spectrophotometry at 264 nm was developed and applied for the selective ibuprofen determination in two-component formulation of ibuprofen and pseudoephedrine-HCl, combined powder which contains ibuprofen in the form of salt with L-arginine and 10% ibuprofen cream. Procedures for ibuprofen determination in complex pharmaceutical preparations by...

The present article describes the potential utility of derivative ultraviolet (UV) spectrophotometric technique to detect petroleum products (gasoline, kerosene and diesel) in fire debris residues. Derivative UV spectra of these petroleum products were recorded in their neat state, and compared with those obtained from fire debris samples in order to distinguish them. Derivative UV spectrophoto...

In this study, zero-, first-, secondand third-order derivative spectrophotometry methods were developed for the determination of metoprolol in pharmaceutical preparations. In zero order spectrophotometry, absorbance values were measured at 276 nm in zero order spectra of solution of metoprolol in methanol in the range of 240-310 nm. In first derivative spectrophotometry, absorbance values were ...

two sensitive spectrophotometric methods are presented for the assay of repaglinide in bulkdrug and in formulations using methyl orange, as reagents. oxidant by reacting with a fixedamount of either methyl orange and measuring the absorbance at 485.2 nm (method-i) andmeasuring the absorbance at 618.9 nm (method-ii). developed method is based on the formationof extractable colored complex of dru...

buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. a mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence.in this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of b...

A spectrophotometric method was developed for simultaneous determination of amlodipine (Aml) and valsartan (Val) without previous separation. In this method amlodipine in methanolic solution was determined using zero order UV spectrophotometry by measuring its absorbency at 360.5 nm without any interference from valsartan.Valsartan spectrum in zero order is totally overlapped with that of amlod...