Deoxynivalenol (DON) is an important Fusarium mycotoxin commonly detected in foods and feeds, which has drawn global attention because of its high contamination level frequency. Applying microbial antagonists to inhibit fungal DON synthesis detoxification into low toxic metabolites are biological approaches eliminate via environment friendly manner. Therefore, it essential review the latest res...

introduction: the fate of xenobiotics that is present, increasing day by day. the increasing fates altered or inhibit the metabolic activities like detoxification and biotransformation. methods: the present study highlights this slow biotransformation and detoxification on the basis of specific enzymes which have a say in assessment of mercuric chloride toxicity and modulation by panax ginseng ...

Members of the cytochrome P450 family are important metabolic enzymes that are present in all metazoans. Genes encoding cytochrome P450s form a multi-gene family, and the number of genes varies widely among species. The enzymes are classified as either biosynthesis- or detoxification-type, depending on their substrates, but their origin and evolution have not been fully understood. In order to ...

Introduction: The fate of xenobiotics that is present, increasing day by day. The increasing fates altered or inhibit the metabolic activities like detoxification and biotransformation. Methods: The present study highlights this slow biotransformation and detoxification on the basis of specific enzymes which have a say in assessment of mercuric chloride toxicity and modulation by Panax ginse...

The liver maintains important homeostatic functions such as metabolism and detoxification. Failure to remove toxic intermediates can cause hepatic damage, fibrosis, even cancer development. This review focuses on acetaldehyde dehydrogenases (ALDHs), a group of key enzymes within the ALDH superfamily with ability convert highly reactive aldehyde substrates corresponding carboxylic acids in NAD(P...

Abstract Streptomycetes have to cope with fluctuating nitrogen conditions in soil. Key enzymes metabolism streptomycetes are the two glutamine synthetases (GSs), GlnA and GlnII. We demonstrated that GlnA3 GlnA4, proteins previously annotated as GSs, involved utilization detoxification of polyamines ethanolamine. Homologs these present pathogenic Actinobacteria promising drug targets. designed a...